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PGY IV (General Surgery) Residents
*Ankit Bharat, M.D. Elizabeth A. Fialkowski, M.D. Amy C. Fox, M.D. Jennifer L. Gnerlich, M.D. Fabian M. Johnston, M.D. T. Elizabeth Robertson, M.D. Marcus C. Tan, M.D. | Ankit Bharat M.D.
Residency in General Surgery
| Medical School
Christian Medical College, Vellore, India
| Awards/Honors
Resident Representative American College of Surgery Missouri Chapter, 2008
J. Maxwell Chamberlain Memorial Award, Society of Thoracic Surgeons, 2008
Resident Teaching Award 2006-2007. Washington University, Dept of Surgery.
Excellence in Research Award. American College of Surgeons 2007.
Wells Jr Research Award Presentation 2007. Washington University, Dept of Surgery.
Young Investigator Award. American Transplant Congress 2007.
NIH Research Travel Award. National Institute of Allergy and Immunology, 2006.
Philip K Caves Award Presentation. International Society of Heart and Lung Transplantation,2006.
Young Investigator Award. American transplant Congress 2005.
Research excellence award. Transplantation Society, 2005.
Research Travel award. American Society of Transplantation, 2005
| Selected or Recent Publications
A Bharat, R Hachem, EP Trulock, G Patterson, B Meyers, T Mohanakumar. Pre-transplant autoantibodies predispose to primary graft dysfunction following lung transplantation and lead to chronic allograft rejection. Accepted.
A Bharat, D Saini, Wei Liu, N Benshoff, T Mohanakumar. Novel mechanisms of virus induced chronic lung allograft rejection. Accepted.
A Bharat, F Gao, J Margenthaler. Tumor Characteristics and Patient Outcomes are Similar Between Invasive Lobular and Mixed Invasive Ductal/Lobular Breast Cancers but Differ From Pure Invasive Ductal Breast Cancers. American Journal of Surgery. In Press.
A Bharat, F Gao, RL Aft, WE Gillanders, TJ Eberlein, J Margenthaler. Predictors of Primary Breast Abscesses and recurrence. World Journal of Surgery, August 8, 2009.
A Bharat, RL Aft, F Gao, JA Margenthaler. Patient and tumor characteristics associated with increased mortality in young women(<40) with breast cancer. J Surg Oncol, Sep 1 2009.
A Bharat, E Kuo, Ramsey, EP Trulock, GA Patterson, BF Meyers, T Mohanakumar. Immunological link between primary graft dysfunction and chronic human lung allograft rejection. Annals of Thoracic Surgery, Jul 2008; 86(1): 189-95.
A Bharat, F Barros, K Narayanan, B Borg, ML Melman, S Shenoy, J Lowell, J Crippin, W Chapman, T Mohanakumar. Characterization of virus-specific T cell immunity in liver allograft recipients with HCV-induced cirrhosis. American Journal of Transplantation, Jun 2008; 8(6), 1214-20.
A Bharat, S Ramachandran, A Golcheneikia, T Mohanakumar. Elevated sCD30 characterizes patients with hepatitis C induced liver allograft cirrhosis. Transplantation, Dec 2007; 84 (12): 1704-7.
A Bharat, K Narayanan, N Benshoff, T Mohanakumar. Characterization of the role of CD8+ T cells in breast cancer immunity following mammaglobin-A DNA vaccination using HLA class-I tetramers. Breast Cancer Research and Treatment 2007 Sep 15 [Epub ahead of print].
A Bharat, D Saini, N Benshoff, J Goodman, NM Desai, WC Chapman, T Mohanakumar. Role of intra-islet endothelial cells in islet allo-immunity. Transplantation, Nov 2007; 84(10): 1316-23.
A Bharat, T Mohanakumar. Allopeptides and the alloimmune responses. Cellular Immunology, Jul 2007; 248(1):31-43.
A Bharat, T Mohanakumar. Evolution of histocompatibility and its significance in organ transplantation. Current opinions in organ transplantation, August 2007; 12(4): 390-393.
| JN Vauthey, D Ribero, EK Abdalla, S Jonas, A Bharat, et al. Outcomes of liver transplantation in 490 patients with hepatocellular carcinoma: validation of a uniform staging after surgical treatment. J Am Coll Surg, May 2007;204(5):1016-27
A Bharat, T Street, A Aloush, B Meyers, EP Trulock, GA Patterson, T Mohanakumar. Early post-transplant inflammation in the development of alloimmunity and chronic human lung allograft rejection. Transplantation, Jan 2007; 83(2): 150-8.
RC Fields, Bharat A, N Steward, A Aloush, BF Meyers, EP Trulock, WC Chapman, GA Patterson, T Mohanakumar. Elevated soluble CD30 correlates with development of bronchiolitis obliterans syndrome following lung transplantation. Transplantation, Dec 2006; 82(12): 1596-1601.
A Bharat, N Steward, A Aloush, EP Trulock, GA Patterson, T Mohanakumar. Induction of IL-10 producing suppressor T cells by CD4+25+ through CTLA-4 signaling. Journal of Immunology Oct 2006; 177(8): 5631-8.
A Bharat, DA Brown, JS Crippin, JE Gould, JA Lowell, S Shenoy, NM Desai, WC Chapman. Pre-liver transplant locoregional adjuvant therapy for hepatocellular patients as a strategy to improve long-term survival. J Am Coll Surg, Oct 2006; 203(4): 411-20.
E Kuo, A Bharat, J Shih, T Street, W Lu, M Walter, GA Patterson, T. Mohanakumar. Role of airway epithelial injury in murine orthotopic tracheal allograft rejection. Annals of Thoracic Surgery, Oct 2006; 82(4):1226-33.
A Bharat, RC Fields, N Steward, EP Trulock, GA Patterson, T Mohanakumar. CD4+25+ regulatory T-cells limit Th1-autoimmunity by inducing IL10 producing T-suppressors in lung transplant patients. Am J Transplant, August 2006, 6(8):1799-1808.
A Bharat, E Kuo, T Goers, W Chapman, T Street, W Lu, M Walter, GA Patterson, T. Mohanakumar. Respiratory viral infection in murine orthotopic tracheal allograft rejection. Annals of Thoracic Surgery, Sep 2006; 82(3):1043-50.
A Bharat, R Fields, T Mohanakumar. Regulatory T-cell mediated transplantation tolerance. Immunological research 33(3): 195-212, 2005.
A Bharat, RC Fields, T Mohanakumar. Cellular regulation of allograft tolerance. ASHI Quarterly, First Quarter 2006; 10-15.
E Kuo, A Bharat, S Dharmarajan, FG Fernandez, GA Patterson, T Mohanakumar. Animal Models for Bronchiolitis Obliterans following human lung transplantation. Immunological Research 33(1): 69-82, 2005.
A Bharat, N Benshoff, B Olack, S Ramachandran, N Desai, T Mohanakumar. A novel in vivo murine model to study islet potency: Engraftment and Function. Transplantation, Jun 15;79(11):1627-30, 2005.
A Bharat, M Vedkumar, HS Subhash, OC Abraham, D Mathai. Antituberculous therapy-induced toxicity. JAPI 2003; 51: 522-4.
S David, R Raju, A Bharat, MK Lalitha, P Ravi. Cutaneous anthrax. AIOC proceedings, 2003. 489-490.
VK Harris, S Harris, A Bharat, S Kuppachi, S Siddique. Bedside localization of misplaced peripherally inserted central catheter. British Journal of Anaesthesia, May 2006.
Harris VK, Woodfield DG, Sukesh CN, Paul C, Bharat A. Geographic distribution of asymptomatic constitutional macrothrombocytopenia in Indian subcontinent. Journal of Thrombosis and Haemostasis 2003, 768-769.
| Selected or Recent Chapters
A Bharat, S Shenoy. Maturation evaluation for dialysis access. In Vascular Access Principles and Practice, 5e. In Press
A Bharat. Overview of the Immune System. In Textbook of Immunolgy, 1ste, Editor: BK Gupta.
| Abstracts/Presentations
A Bharat, E Kuo, G Patterson, BF Meyers, T Mohanakumar. Novel Mechanisms Of Virus Induced Chronic Human Lung Allograft Rejection. 46th Annual STS Meeting, Jan 2010, Ft Lauderdale, Florida.
A Bharat, E Kuo, G Patterson, BF Meyers, T Mohanakumar. Pre-transplant Autoantibodies Lead To Primary Graft Dysfunction And Predispose To Bronchiolitis Obliterans Syndrome. 46th Annual STS Meeting, Jan 2010, Ft Lauderdale, Florida.
A Bharat, R Hachem, E Trulock, B Meyers, G Patterson, W Chapman, T Mohanakumar. Locoregional dendritic cells from virus infected recipients can convert CD4+CD25+Foxp3+ regulatory T cells into Th17-cells and promote autoimmunity. 95th Clinical Congress American Colleege of Surgeons, Oct 2009, Chicago, Illinois.
A Bharat, F Gao, R L Aft, W E Gillanders, T J Eberlein, J A Margenthaler. Patient and Tumor Characteristics in young women (<40 years) with breast cancer that results in increased mortality. 8th Annual meeting of American Society of Breast Surgeons, Apr 30 – May 4, 2008, New York.
A Bharat, F Gao, R L Aft, W E Gillanders, T J Eberlein, J A Margenthaler. Predictors of primary breast abscesses and recurrence. 8th Annual meeting of American Society of Breast Surgeons, Apr 30 – May 4, 2008, New York.
A Bharat, E Kuo, R Hachem, EP Trulock, GA Patterson, BF Meyers, T Mohanakumar. Immunological Link Between Primary Graft Dysfunction (PGD) and Bronchiolitis Obliterans Syndrome (BOS). 2008 Annual STS Meeting, Jan 28-31, Fort Lauderdale.
A Bharat, R C Fields, E Kuo, M Walter, W C Chapman, G A Patterson, T Mohanakumar. Respiratory viral infections predispose to chronic human lung allograft rejection by inducing apoptosis of CD4+CD25+foxp3+ regulatory T cells through airway epithelial cells. Surgical Forum, 2007 ACS Clinical Congress, Oct 7-11, New Orleans.
A Bharat, J Goodman, N Desai, WC Chapman, T Mohanakumar. Accommodation of intraislet endothelial cells confers resistance to hyperacute islet allograft rejection. Surgical Forum, 2007 ACS Clinical Congress, Oct 7-11, New Orleans.
A Bharat, E Kuo, W Liu, M Walter, S Shenoy, GA Patterson, T Mohanakumar. Infection of airway epithelial cells by respiratory viruses predisposes to chronic lung allograft rejection by inducing regulatory T-cell apoptosis. 2007 American Transplant Congress Meeting, San Francisco, May 5-9.
A Bharat, J Goodman, NM Desai, S Shenoy, WC Chapman, T Mohanakumar. Donor-MHC specific sensitization is detrimental to islet allograft survival. 2007 American Transplant Congress Meeting, San Francisco, May 5-9.
| A Bharat, K Narayanan, N Benshoff, JR Dietz, W Gillanders, T Mohanakumar. Inducing Mammaglobin-A specific HLA class I tetramer positive CD8+ cytotoxic T lymphocytes against breast cancer by DNA vaccination. Oral. Surgical Forum, 92nd ACS Annual Clinical Congress Meeting, Chicago, October 8-12, 2006.
A Bharat, RC Fields, EP Trulock, GA Patterson, T Mohanakumar. Dysregulation of autoimmunity to collagen V and development of BOS following human lung transplantation. Oral. Surgical Forum, 92nd ACS Annual Clinical Congress Meeting, Chicago, October 8-12, 2006.
A Bharat, K Narayanan, R Fields, E P Trulock, W C Chapman, G A Patterson, and T Mohanakumar. Early post-transplant elevation of pro-inflammatory mediators leads to donor HLA class II alloimmunity and chronic rejection in lung transplant patients. Poster. World Transplant Congress meeting, Boston, July 22nd- 27th, 2006.
A Bharat, R Fields, E P Trulock, G A Patterson, and T Mohanakumar. Regulation of autoimmunity by CD4+CD25+ T-cells (T-regs) following lung transplantation. Oral. World Transplant Congress meeting, Boston, July 22nd- 27th, 2006.
A Bharat, K Narayanan, J Goodman, N Desai, W C Chapman, and T Mohanakumar. Role of endothelial cells in promoting islet allograft survival. Poster. World Transplant Congress meeting, Boston, July 22nd- 27th, 2006.
RC Fields, A Bharat, WC Chapman, EP Trulock, GA Patterson, T Mohanakumar. Elevated soluble CD30 correlates with onset of bronchiolitis obliterans syndrome in lung transplant patients. Oral (Awarded Young Investigator Award). World Transplant Congress meeting, Boston, July 22nd- 27th, 2006.
RC fields, A Bharat, W Liu, WC Chapman, GA Patterson, T Mohanakumar. Tolerance transfer from isograft to allograft. Poster. World Transplant Congress meeting, Boston, July 22nd- 27th, 2006.
A Bharat, JA Lowell, JS Crippin, NM Desai, S Shenoy, ML Melman, KM Korenblat, DB Brown, MD Jendrisak, WC Chapman. Pre-transplant locoregional adjuvant therapy for hepatocellular patients as a strategy to improve long-term survival following liver transplantation. AHPBA Annual Meeting, Florida, March 9th -12th, 2006.
A Bharat, RC Fields, A Aloush, EP Trulock, GA Patterson, T Mohanakumar. CD4+CD25+ T-cells mediated regulation of autoimmunity following human lung transplantation. Oral. 26th Annual Meeting International Society of Heart and Lung Transplantation, Madrid, Spain. April 5th-8th 2006.
A Bharat, T Street, K Narayanan, R C Fields, N Steward, A Aloush, EP Trulock, GA Patterson, T Mohanakumar. Pro-inflammatory Th1-cytokines and HLA class-II alloimmunity may predispose to chronic human lung allograft rejection. Oral. 26th Annual Meeting International Society of Heart and Lung Transplantation, Madrid, Spain. April 5th-8th 2006.
| RC Fields, A Bharat, W Liu, GA Patterson, T Mohanakumar. Dendritic cell and regulatory T-cells interactions in a murine model of obliterative bronchiolitis. Oral. 26th Annual Meeting International Society of Heart and Lung Transplantation, Madrid, Spain. April 5th-8th 2006.
A Bharat, K Narayanan, N Benshoff, N Desai, WC Chapman, T Mohanakumar. “Accommodation” to promote post-transplant islet cell survival. 9th Basic Science Symposium, La Baule, France June 19th -22nd,2005.
A Bharat, EP Trulock, GA Patterson, T Mohanakumar. Loss of induction of T-regulatory type 1 activity by CD4+25+ natural T-regs can lead to the development of autoimmunity in patients with chronic human lung allograft rejection. 9th Basic Science Symposium, La Baule, France, June 19th -22nd.
A Bharat, A Aloush, EP Trulock, GA Patterson, T Mohanakumar. Loss of CD4+25+ natural T-regs can lead to collagen type V specific autoimmunity in patients with chronic human allograft rejection. Oral. 2005 American Transplant Congress Meeting, Seattle, May 21st-5.
A Bharat, A Aloush, EP Trulock, GA Patterson, T Mohanakumar. Autoimmunity to collagen type V can contribute to chronic rejection in human lung allografts. Oral. 25th Anniversary Meeting International Society of Heart and Lung Transplantation, Philadelphia, April 5th-9th 2005.
A Bharat, A Aloush, EP Trulock, GA Patterson, T Mohanakumar. Hypersensitivity to self-proteins may lead to chronic rejection after human lung transplantation. Oral. 30th Annual meeting of American Society of Histocompatibility and Immunogenetics. San Antonio, TX. Oct 1st-6th 2004.
A Bharat, N Benshoff, B Olack, S Ramachandran, N Desai, T Mohanakumar. A unique murine model to test islet potency: engraftment and function. Oral. 30th Annual meeting of American Society of Histocompatibility and Immunogenetics San Antonio, TX. Oct 1st-6th 2004.
A Bharat, M Vedkumar, HS Subhash, OC Abraham, D Mathai. Antituberculous therapy-induced toxixity. Poster. Asian American International Medical Conference, Jan 3-5, 2003, Goa, India.
S David, R Raju, A Bharat. Cutaneous Anthrax. Oral 61st Annual Conference of All Indian Ophthalmology Society, Jan 16-19, 2003, New Delhi, India.
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