Jun Guo, Ph.D.

Appointment
Assistant Professor of Surgery
Division of Pediatric Surgery
Washington University School of Medicine

Email
guoj@wudosis.wustl.edu  

Phone
(314) 454-6022

Fax
(314) 454-2442

Credentials
Ph.D., Neurobiology, Shanghai Medical University, Shanghai, P. R. China, 2000.

Publications, Most recent
Sheng G, Bernabe KQ, Guo J, Warner BW. Epidermal growth factor receptor-mediated proliferation of enterocytes requires p21waf1/cip1 expression. Gastroenterology. 2006;131(1):153-164.

Guo J, Sheng G, Warner BW. Epidermal growth factor-induced rapid retinoblastoma phosphorylation at Ser780 and Ser795 is mediated by ERK1/2 in small intestine epithelial cells. Journal of Biological Chemistry. 2005;280(43):35992-35998. Epub 2005 Aug 26

Stehr W, Bernal NP, Erwin CR, Bernabe KQ, Guo J, Warner BW. Roles for p21waf1/cip1 and p27kip1 during the adaptation response to massive intestinal resection. Am J Physiol Gastrointest Liver Physiol. 2006;290(5):G933-G941. Epub 2005 Dec 1.

Salazar G, Craige B, Wainer BH, Guo J, De Camilli P, Faundez V. Phosphatidylinositol-4-Kinase Type II Alpha is a component of AP-3-derived vesicles. Molecular Biology of the Cell. 2005;16(8):3692-3704. Epub 2005 Jun 8

Lacas-Gervais S, Guo J, Strenzke N, Scarfone E, Kolpe M, Jahkel M, De Camilli P, Moser T, Rasband MN, Solimena M. BetaIVSigma1 spectrin stabilizes the nodes of Ranvier and axon initial segments. Journal of Cell Biology. 2004;166(7):983-990.

Guo J, Wenk MR, Pellegrini L, Onofri F, Benfenati F, De Camilli P. Phosphatidylinositol 4-kinase type IIalpha is responsible for the phosphatidylinositol 4-kinase activity associated with synaptic vesicles. Proceedings of the National Academy of Sciences U S A. 2003;100(7):3995-4000.

Di Paolo G, Pellegrini L, Letinic K, Cestra G, Zoncu R, Voronov S, Chang S, Guo J, Wenk M, De Camilli P. Recruitment and regulation of PIP kinase type 1 gamma by the FERM domain of talin. Nature. 2002;420:85-89.

Ort T, Voronov S, Guo J, Zawalich K, Froehner SC, Zawalich W, Solimena M. Dephosphorylation of beta2-syntrophin and Ca2+/mu-calpain-mediated cleavage of ICA512 upon stimulation of insulin secretion. EMBO Journal. 2001;20(15):4013-4023.

Cen B, Yu Q, Guo J, Wu Y, Ling K, Cheng Z, Ma L, Pei G. Direct binding of beta-arrestins to two distinct intracellular domains of the delta opioid receptor. Journal of Neurochemistry. 2001;76(6):1887-1894.

Xiang B, Yu GH, Guo J, Chen L, Hu W, Pei G, Ma L. Heterologous activation of protein kinase C stimulates phosphorylation of delta-opioid receptor at serine 344 and this results in beta-arrestin- and clathrin-mediated receptor internalization. Journal of Biological Chemistry. 2001;276(7):4709-4716.

Guo J, Wu Y, Zhang W, Zhao J, Devi LA, Pei G, Ma L. Identification of G protein-coupled receptor kinase 2 phosphorylation sites responsible for agonist-stimulated delta-opioid receptor phosphorylation. Molecular Pharmacology. 2000;58(5):1050-1056.

Zhou TH, Ling K, Guo J, Zhou H, Wu YL, Jing Q, Ma L, Pei G. Identification of a human brain-specific isoform of mammalian STE20-like kinase 3 that is regulated by cAMP-dependent protein kinase. Journal of Biological Chemistry. 2000;275(4):2513-2519.

Related Areas:
Washington University Division of Pediatric Surgery