Washington University School of Medicine   |  
  

Christopher R. Erwin Ph.D.


Pediatric Surgery

Associate Professor of Surgery
Division of Pediatric Surgery
Medical Education
Ph.D., Genetics, University of Iowa, Iowa City, IA, 1978-1983
Selected or Recent Publications
Warner BB, Ryan AL, Seeger K, Leonard AC, Erwin C, Warner BW. Ontogeny of salivary epidermal growth factor and necrotizing enterocolitis. Journal of Pediatrics. 2007;150(4):358-363.

Warner BW, Erwin CR. Critical roles for EGF receptor signaling during resection-induced intestinal adaptation. Journal of Pediatric Gastroenterology and Nutrition. 2006;43 Suppl 1:S68-S73.

Stehr W, Bernal NP, Erwin CR, Bernabe KQ, Guo J, Warner BW. Roles for p21waf1/cip1 and p27kip1 during the adaptation response to massive intestinal resection. American Journal of Physiology (Gastrointestinal and Liver Physiology). 2006;290(5):G933-G941.

Bernal NP, Stehr W, Coyle R, Erwin CR, Warner BW. EGF receptor signaling regulates BAX and Bcl-W expression and apoptotic responses during intestinal adaptation in mice. Gastroenterology. 2006;130(2):412-423.

Bernal NP, Stehr W, Profitt P, Erwin CR, Warner BW. Combined pharmacotherapy that increases proliferation and decreases apoptosis optimally enhances intestinal adaptation. Journal of Pediatric Surgery. 2006;41(4):719-724.

Stehr W, Bernabe KQ, Bernal NP, Erwin CR, Warner BW. Absent STAT1 expression perturbs adaptation and apoptosis after massive intestinal resection. Journal of Pediatric Surgery. 2006;41(4):713-718.

Erwin CR, Jarboe MD, Sarotor MA, Medvedovic M, Warner BW, Bates MD. Developmental characteristics of adapting small intestine crypt cells. Gastroenterology. 2006;130(4):1324-1332.

Stehr W, Mercer TI, Bernal NP, Erwin CR, Warner BW. Opposing roles for p21waf1/cip1 and p27kip1 in enterocyte differentiation, proliferation, and migration. Surgery. 2005;138(2):187-194.

Prasad V, Boivin GP, Liu LH, Erwin CR, Warner BW, Shull GE. Haploinsufficiency of Atp2a2, encoding the sarco/endoplasmic reticulum Ca2+-ATPase isoforms 2, predisposes mice to squamous tumors, defining a novel mode of cancer susceptibility. Cancer Research. 2005;65(19):8655-8661.

Bernal NP, Stehr W, Zhang Y, Profitt S, Erwin CR, Warner BW. Evidence for active Wnt signaling during postresection intestinal adaptation. Journal of Pediatric Surgery. 2005;40(6):1025-1029.

Jarboe MD, Juno RJ, Stehr W, Bernal NP, Profitt S, Erwin CR, Warner BW. Epidermal growth factor receptor signaling regulates goblet cell production after small bowel resection. Journal of Pediatric Surgery. 2005;40:92-97.

Knott AW, Juno RJ, Jarboe MD, Profitt SA, Erwin CR, Smith EP, Fagin JA, Warner BW. Smooth muscle overexpression of IGF-1 induces a novel adaptive response to small bowel resection. American Journal of Physiology (Gastrointestinal and Liver Physiology). 2004;287(3):G562-G570.

Jarboe MD, Juno RJ, Bernal NP, Knott AW, Zhang Y, Erwin CR, Warner BW. Bax deficiency rescues resection-induced enterocyte apoptosis in mice with perturbed EGF receptor function. Surgery. 2004;136(2):121-126.

Juno RJ, Knott AW, Profitt S, Jarboe MD, Zhang Y, Erwin CR, Warner BW. Preventing enterocyte apoptosis after massive small bowel resection does not enhance adaptation of the intestinal mucosa. Journal of Pediatric Surgery, 2004;39(6):907-911.

Erwin CR, Warner BW. Hirschsprung lost his nerve. Gastroenterology. 2003;125:1900-1902.

Pub Med page for Christopher R. Erwin, Ph.D.