Washington University School of Medicine   |  
  

Alex A. Kane M.D.


Plastic and Reconstructive Surgery

Associate Professor, Surgery
Division of Plastic and Reconstructive Surgery
Director, Cleft Palate and Craniofacial Deformities Institute
Board Certification
Plastic and Reconstructive Surgery -- Board Certified
Areas of Specialty and Clinical Interest
Dr. Kane specializes in craniofacial surgery, pediatric plastic and reconstructive surgery, and facial trauma. Other areas of clinical interest include cleft lip and cleft palate.

Dr. Kane also performs cosmetic surgery procedures at the Washington University Cosmetic Surgery Institute.
Medical School
Dartmouth Medical School, Hanover, New Hampshire, 1991
Postdoctoral Education
Residency: General Surgery, Washington University School of Medicine, St. Louis, Missouri, 1994

Residency: Plastic Surgery, Washington University School of Medicine, St. Louis, Missouri, 1997

Chief Resident: Plastic Surgery, Washington University School of Medicine, St. Louis, Missouri, 1998

Fellowship: Craniofacial Surgery, Chang-Gung Memorial Hospital, Taipei, Taiwan, Republic of China, 1999

Fellowship: Craniofacial Imaging, National Laboratory for Diagnostic Research, Bethesda, Maryland, 1999
Patients Seen At
St. Louis Children's Hospital
One Children's Place, Suite 1A
St. Louis, MO 63110
Patient Appointments
(314) 362-7388 or (800) 283-5848
Hospital Affiliations
St. Louis Children's Hospital
Barnes-Jewish Hosptial
Funding
NIH Grant 1R01DE013813-01A1, “Neurobehavioral Correlates of Craniosynostosis”. Principal Investigator: Matthew Speltz. National Institute of Dental and Craniofacial Research. Project Start: 9/01. Project End: 6/06. 10% time commitment.

NIH Grant 5P60DE13078-020006, “Genotypic And Phenotypic Variability In Craniosynostosis”. Principal Investigator: Joan T. Richtsmeier. National Institute of Dental and Craniofacial Research. Project Start: 8/99. Project End: 7/04. 10% time commitment.
Awards/Honors
Paul M. Weeks Resident Teaching Award, Division of Plastic and Reconstructive Surgery, Washington University School of Medicine, 2003

Visiting Professor, New York University, Institute for Reconstructive Plastic Surgery, April 1-4, 2002

The Owen Cole Memorial Award, Best Scientific Paper for Junior Investigator, 9th International Congress on Cleft Palate and Related Craniofacial Anomalies, Göteborg, Sweden, June 25-29, 2001

National Institutes of Health. Intramural Research Training Award. Bethesda, MD, 1999

Junior Clinical Research Award, Plastic Surgery Educational Foundation Scholarship Contest, 1998

Washington University Division of Plastic Surgery. Best Resident Clinical Paper of Year. 1998

St. Louis Area Society of Plastic Surgeons. First Place, Resident Paper Competition. 1998

Washington University Division of Plastic Surgery. Best Resident Clinical Paper of Year. 1997

St. Louis Area Society of Plastic Surgeons. First Place, Resident Paper Competition. 1996

United Nations Institute/Dickey Endowment Award to attend World Health Organization Summer Internship, Division of Emergency Preparedness. Geneva, Switzerland. 1989
Selected or Recent Publications
Shum L, Wang X, Kane AA, Nuckolls GH. BMP promotes chondrocyte proliferation and hypertrophy in the endochondral cranial base. International Journal of Developmental Biology. (in press)

Becker DB, Petersen JD, Dundulis JA, Kane AA, Cradock MM, Marsh JL. Speech, cognitive and behavioral function in non-syndromic craniosynostoses. Pediatrics. (in submission)

Dundulis JA, Becker DB, Govier DP, Marsh JL, Kane AA. Coronal ring involvement in patients treated for unilateral coronal craniosynostosis. Plastic and Reconstructive Surgery. 2004;114(7):1695-1703.

Becker DB, Pilgram T, Marty-Grames L, Govier DP, Marsh JL, Kane AA. Accuracy in identification of patients with 22q11.2 deletion by likely care providers using facial photographs. Plastic and Reconstructive Surgery. 2004;114(6):1367-1372.

Petersen JD, Becker DB, Fundakowski CE, Marsh JL, Kane AA. A novel management for calcifying cephalohematoma. Plastic and Reconstructive Surgery. 2004;113(5):1404-1409.

Lo LJ, Kane AA, Chen YR. Reconstruction of the secondary bilateral cleft lip and nasal deformity: Abbe flap revisited. Plastic and Reconstructive Surgery. (accepted for publication)

Perlyn CA, Schmelzer RE, Sutera SP, Kane AA, Govier D, Marsh JL. Effect of distraction osteogenesis of the mandible on upper airway volume and resistance in children with micrognathia. Plastic and Reconstructive Surgery. 2002;109(6):1809-1818.

Kane AA, Butman JA, Mullick R, Skopec M, Choyke P. A new method for the study of velopharyngeal function using gated MRI. Plastic and Reconstructive Surgery. 2002;109(2):472-481.

Perlyn CA, Kane AA, Marsh JL, Koppel P, Clark KW, Vannier MW, Christensen GE, Knapp R, Lo LJ, Govier D. The craniofacial anomalies archive at St. Louis Children's Hospital: 20 years of craniofacial imaging experience. Plastic and Reconstructive Surgery. 2001;108(7)1862-1870.

Kane AA, Liao YF, Lo LJ, Huang CS, Huang LM, Chen YR, Noordhoff MS. A cephalometric study of facial growth in van der Woude Syndrome. Cleft Palate-Craniofacial Journal. 2002;39(2)219-225.

Perlyn CA, Marsh JL, Pilgram TK, Kane A. Plasticity of the endocranial base in nonsyndromic craniosynostosis. Plastic and Reconstructive Surgery. 2001;108(2):294-301.

Aldridge K, Marsh JL, Perlyn CA, Richtsmeier JT, Kane AA. Quantification of the impact of isolated craniosynostosis on central nervous system morphology. Transactions of the 9th International Congress on Cleft Palate and Related Craniofacial Anomalies. Goteborg, Sweden, June 2001.

Kane AA, Lo LJ, Chen YR, Hsu KH, Noordhoff MS. The course of the inferior alveolar nerve in the normal human mandibular ramus and in patients presenting for cosmetic reduction of the mandibular angles. Plastic and Reconstructive Surgery. 2000;106(5):1162-1174; discussion 1175-1176.

Kane AA, Lo LJ, Yen BD, Chen YR, Noordhoff MS. The effect of hamulus fracture on the outcome of palatoplasty: A preliminary report of a prospective, alternating study. Cleft Palate-Craniofacial Journal. 2000;37(5):506–511.

Kane AA, Marsh JL, Kim YO, Eaton A, Pilgram T, Vannier MW, Christensen GE, Kreiborg S, Larsen P, Zonneveld F. Quantification of facial osseous dysmorphology in untreated unilateral coronal craniosynostosis. Plastic and Reconstructive Surgery. 2000;106(2):251-258.

Pub Med page for Alex A. Kane, M.D.
Selected or Recent Chapters
Marsh JL, Gurley J, Kane AA. Non-syndromic Craniosynostosis. In: Mathes SJ, Hentz VR (eds.). Plastic Surgery. Second edition. New York: W.B. Saunders and Company. (in press)

Kane AA, Lo LJ, Marsh JL. Computer-Aided Craniofacial Surgery. In: Citardi MJ (ed.). Computer-aided Otorhinolaryngology-Head and Neck Surgery. New York: Marcel-Dekker Publishers; 2002.
Presentations
Kane AA, Amini AA, Bae T, Chen Y, Foster G, Govier DP, Smith K, Zheng J. A New Method for Kinematic Evaluation of Velar Motion During Speech Using Gated Radiofrequency Tagged MRI. American Cleft Palate-Craniofacial Association. April 8-13, 2003. Asheville, N.C.

Becker DB, Dundalis J, Govier DP, Marsh JL, Kane AA. Distribution of Synostosis in Sutures Contributing to the Coronal Ring in Patients Receiving Treatment for Unilateral Coronal Synostosis. American Cleft Palate-Craniofacial Association. April 8-13, 2003. Asheville, N.C.

Becker DB, Petersen JD, Dundalis JA, Kane AA, Cradock MM, Marsh JL. Cognitive and Behavioral Function In Non-Syndromic Craniosynostoses. American Cleft Palate-Craniofacial Association. April 8-13, 2003. Asheville, N.C.

Becker DB, Marty-Grames L, Govier DP, Pilgram TK, Gurley JM, Marsh JL, Kane AA. Accuracy in Identification of Patients with 22Q11.2 Deletion by Likely Care Providers Using Facial Photographs. American Cleft Palate-Craniofacial Association. April 8-13, 2003. Asheville, N.C.

Becker DB, Petersen JD, Fundakowski CE, Marsh JL, Kane AA. Cranial Molding Helmet Therapy for Calcifying Cephalohematoma. American Cleft Palate-Craniofacial Association. April 8-13, 2003. Asheville, N.C.

Govier DP, Kane AA, Marsh JL, Perlyn CA, Schmelzer RE. Appearance of Sutural Patency in Lambdoid Synostosis is Dependent Upon Plane of CT Acquisition. American Cleft Palate-Craniofacial Association. April 8-13, 2003. Asheville, N.C.

Gurley JM, Morin DJ, Kane AA, Scheve SV, Marsh JL. Custom-Designed Cleft/Craniofacial Database (Teaching Course). American Cleft Palate-Craniofacial Association. April 8-13, 2003. Asheville, N.C.

Wang X, Shum L, Kane AA, Nuckolls GH. BMP Regulates Cranial Base Development By Promoting Cartilage Matrix Accumulation And By Inducing Chondrocyte Hypertrophy. Orthopaedic Research Society Meeting. February 2-5, 2003. New Orleans, LA.

Kane AA, Gruss JS. Craniosynostosis Specialty Session Moderator. American Cleft Palate-Craniofacial Association. April 30-May 2, 2002. Seattle, WA.

Kane AA, Marsh JL. A Report of Two Cases of Frontosphenoidal Synostosis. American Cleft Palate-Craniofacial Association. April 30-May 2, 2002. Seattle, WA.

Schmelzer RE, Perlyn CA, Kane AA, Gurley JM, Govier DP, Marsh JL. A Comparison of the Effects on the Endocranial Base for Two Surgical Approaches in the Treatment of Sagittal Craniosynostosis. American Cleft Palate-Craniofacial Association. April 30-May 2, 2002. Seattle, WA.

Kane AA, Butman JA, Mullick R, Skopec M, Choyke P. A New Method for the Study of Velopharyngeal Function Using Gated MRI. 9th International Congress on Cleft Palate and Related Craniofacial Anomalies, Göteborg, Sweden, June 25-29, 2001.

Darvann TA, Hermann NV, Huebener DV, Nissen RJ, Kane AA, Schlesinger JK, Dalsgaard F, Kreiborg S, Marsh JL. The CT-scan Method of 3D Form Description of the Maxillary Arch: Validation and an Application. 9th International Congress on Cleft Palate and Related Craniofacial Anomalies, Göteborg, Sweden, June 25-29, 2001.

Richtsmeier JT, Aldridge K, Marsh JL, Kane AA, Perlyn CA. Quantification of the Impact of Isolated Craniosynostosis on Central Nervous System Morphology. 9th International Congress on Cleft Palate and Related Craniofacial Anomalies, Göteborg, Sweden, June 25-29, 2001.

Kane AA, DeLeon VB, Valeri C, Richtsmeier JT, Lo LJ. The Effects of Growth and Lip Repair Upon Osseous Facial Morphology in Unilateral Complete Cleft Lip and Palate: An Analysis of Longitudinal CT Data. 9th International Congress on Cleft Palate and Related Craniofacial Anomalies, Göteborg, Sweden, June 25-29, 2001.
Abstracts
Conroy G, Kane AA, Seidler H, Weber G, Tobias P. Endocranial capacity of Stw 505(“Mr. Ples”), a large new hominid cranium from Sterkfontein. American Journal of Physical Anthropology. Supp 26 1998:69-70.
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