Jun Guo, PhD
Ph.D., Neurobiology, Shanghai Medical University, Shanghai, P. R. China, 2000
Research associate with Dr. Brad Warner, the leading authority in the field of intestinal adaptation following massive small bowel resection.
One of focuses has been generating an in vitro cell culture system to mimic the condition in vivo to understand the signal transduction pathway of EGFR, and further to determine the mechanism for enhanced intestinal adaptation by EGF/EGFR axis stimulation.
Dr. Guo utilizes a mouse surgical model to study the adaptive growth in the remnant bowel after massive resection. He is interested in enterocytes proliferation, differentiation and apoptosis and their role in the regenerative growth after resection. He is also interested in type 2 immunity in the small intestine and is actively pursuing how to promote small intestine lengthening via activating type 2 immunity in the gut.