Radhika K. Smith, MD


Specialty Areas

Disease of the colon, rectum, and anus including such pathology as colon and rectal polyps and cancer, constipation, Crohn’s disease and ulcerative
colitis, diverticulitis, fecal incontinence, hemorrhoids and other anorectal disorders, pelvic floor disorders and rectal prolapse

Common Procedures

  • Hemorrhoidal banding
  • Hemorrhoidal excision
  • Anoscopy Internal-lateral sphincterotomy
  • Botox Injection
  • Repair of fistula and fissure
  • Laparoscopic or open rectal prolapse repair
  • Treatment of proctitis
  • Solitary rectal ulcer syndrome
  • Proctodynia
  • Appendectomy
  • Laparoscopic and open colectomy
  • Proctocolectomy with ileal pouch anal anastomosis
  • Surgery for polyps
  • Colonoscopy
  • Stricturoplasty
  • Minimally invasive resections for Crohn’s Disease
  • Laparoscopic small intestinal resection
  • InterStim Therapy
  • Anal ultrasound, manometry, and EMG

Common Diagnoses Treated

  • Anal cancer
  • Colon cancer
  • Colon polyps
  • Colorectal cancer
  • Constipation
  • Crohn’s disease
  • Diverticulitis
  • Fecal incontinence
  • Fissures
  • Hemorrhoids
  • Intestinal stomas
  • Pelvic floor disorders
  • Pilonidal cysts
  • Rectal cancer
  • Rectal prolapse
  • Ulcerative colitis


Board Certifications

American Board of Surgery

American Board of Colon and Rectal Surgery


Medical School: University of Missouri, Kansas City, MO, St. Louis, MO 2010


2015 General Surgery Residency, Temple University, Philadelphia, PA


2016 Colorectal Surgery Fellowship, Cleveland Clinic Florida, Weston, FL

Professional Memberships

American Society of Colon and Rectal Surgeons

American College of Surgeons

American Osteopathic Association

The Society for Surgery of the Alimentary Tract

Awards and Honors

2020 – Academic Medical Leadership Development Program For Physicians and Scientists

2017 – University of Chicago Excellence in Teaching

2015 – H. Tylor Caswell Resident Teaching Award

2015 – Eva Lotzova Memorial Basic/Translational Research Award

2019 – ASCRS Best Paper Award for the general surgery forum


Areas of Research Interest

Colorectal Cancer

Inflammatory bowel disease


Clinical Trials

Site Primary Investigator, 231925 TiGenix ADMIRE II CD study. Stem cell therapy for fistulizing perianal Crohn’s disease.


Sossenheimer PH, Glick LR, Dachman AH, Skowron KB, Rubin MA, Umanskiy K, Smith R, Cannon LM, Hurst RD, Cohen RD, Hyman NH, Rubin DT. Abnormal Pouchogram Predicts Pouch Failure Even in Asymptomatic Patients. Dis Colon Rectum. 2019 Apr;62(4):463-469

Eisenstein S, Holubar SD, Hilbert N, et al. The ACS National Surgical Quality Improvement Program-Inflammatory Bowel Disease Collaborative: Design, Implementation, and Validation of a Disease-specific Module. Inflamm Bowel Dis. 2019;25(11):1731–1739. doi:10.1093/ibd/izz044

Rosen DR, Wolfe RC, Damle A, Atallah C, Chapman WC Jr, Vetter JM, Mutch MG, Hunt SR, Glasgow SC, Wise PE, Smith RK, Silviera ML. Thoracic Epidural Analgesia: Does It Enhance Recovery? Dis Colon Rectum. 2018 Dec;61(12):1403-1409

Chadi SA, Malcomson L, Ensor J, Riley RD, Vaccaro CA, Rossi GL, Daniels IR, Smart NJ, Osborne ME, Beets GL, Maas M, Bitterman DS, Du K, Gollins S, Sun Myint A, Smith FM, Saunders MP, Scott N, O’Dwyer ST, de Castro Araujo RO, Valadao M, Lopes A, Hsiao CW, Lai CL, Smith RK, Paulson EC, Appelt A, Jakobsen A, Wexner SD, Habr-Gama A, Sao Julião G, Perez R, Renehan AG. Factors affecting local regrowth after watch and wait for patients with a clinical complete response following chemoradiotherapy in rectal cancer (InterCoRe consortium): an individual participant data meta-analysis. Lancet Gastroenterol Hepatol. 2018 Dec;3(12):825-836

Yamada A, Komaki Y, Patel N, Komaki F, Aelvoet AS, Tran AL, Pekow J, Dalal S, Cohen RD, Cannon L, Umanskiy K, Smith R, Hurst R, Hyman N, Rubin DT, Sakuraba A. The Use of Vedolizumab in Preventing Postoperative Recurrence of Crohn’s Disease. Inflamm Bowel Dis. 2018 Feb 15;24(3):502-509.

Lightner AL, McKenna NP, Tse CS, Hyman N, Smith R, Ovsepyan G, Fleshner P, Crowell K, Koltun W, Ferrante M, D’Hoore A, Lauwers N, Verstockt B, Spinelli A, DiCandido F, Raffals LE, Mathis KL, Loftus EV Jr. Postoperative Outcomes in Ustekinumab-Treated Patients Undergoing Abdominal Operations for Crohn’s Disease. J Crohns Colitis. 2018 Mar 28;12(4):402-407

Anyane-Yeboa A, Yamada A, Haider H, Wang Y, Komaki Y, Komaki F, Pekow J, Dalal S1, Cohen RD, Cannon L, Umanskiy K, Smith R, Hurst R, Hyman N, Rubin DT, Sakuraba A. A comparison of the risk of postoperative recurrence between African-American and Caucasian patients with Crohn’s disease. Aliment Pharmacol Ther. 2018 Nov;48(9):933-940.

Yamada A, Komaki Y, Patel N, Komaki F, Pekow J, Dalal S, Cohen RD, Cannon L, Umanskiy K, Smith R, Hurst R, Hyman N, Rubin DT, Sakuraba A. Risk of postoperative complications among inflammatory bowel disease patients treated preoperatively with vedolizumab. American Journal of Gastroenterology. Am J Gastroenterol. 2017 Sep;112(9):1423-1429 9. Smith R, Maron DJ. Laparoscopy for Benign Diseases of the Colon. Clin Colon Rectal Surg. 2017 Apr;30(2):91-98.

Koller SE, Bauer KW, Egleston BL, Smith R, Philp MM, Ross HM, Esnaola NF. Comparative Effectiveness and Risks of Bowel Preparation Before Elective Colorectal Surgery. Ann Surg. 2017 11. Smith RK, Fry RD, Mahmoud NN, Paulson EC. Surveillance after neoadjuvant therapy in advanced rectal cancer with complete clinical response can have comparable outcomes to total mesorectal excision. Int J Colorectal Dis. 2015 Jun;30(6):769-74.

Smith RK, Paulson EC. Perianal fistula in Crohn’s Disease. Semin Colon Rectal Surg. 2014 Dec; 25(4): 216-20.

Smith RK, Broach RB, Hedrick TL, Mahmoud NN, Paulson EC. The impact of body mass index on post-operative outcomes in patients undergoing proctectomy for rectal cancer: a NSQIP analysis. Dis Colon Rectum. 2014 Jun;57(6):687-93.

Heffernan DS, Thakkar RK, Monaghan SF, Ravindran R, Adams CA, Kozloff MS, Gregg SC, Connolly MD, Machan JT, Ciof WG. Normal presenting vital signs are unreliable in geriatric blunt trauma victims. J Trauma. 2010 Oct; 69(4):813-20.


Hospital Affiliations

Barnes-Jewish Hospital

Barnes-Jewish West County Hospital

Patients Seen At

Barnes-Jewish West County Hospital
Medical Building 4
1044 North Mason Road
Suite 310
St. Louis, MO  63141
Telephone: 314-454-7177
Fax: 888-425-7946

Center for Advanced Medicine–South County
5201 Midamerica Plaza
St. Louis, MO 63129
Telephone: 314-454-7177
Fax: 888-425-7946


To request an appointment with Dr. Smith, please call (314) 454-7177 or request an appointment online.