Paul E. Wise, MD

Paul E. Wise, MD

Professor of Surgery
Section of Colon and Rectal Surgery
Division of General Surgery
Vice Chair for Education, Department of Surgery
Director, Inherited Colorectal Cancer and Polyposis Registry

Specialties

  • Inherited colorectal cancer and hereditary colorectal cancer syndromes (Lynch syndrome, hereditary nonpolyposis colorectal cancer (HNPCC) familial adenomatous polyposis (FAP), polyposis syndromes)
  • Colon cancer
  • Rectal cancer
  • Anal cancer
  • Colon and rectal polyps
  • Inflammatory bowel disease (Crohn’s disease and ulcerative colitis)
  • Other disease of the colon and rectum (diverticulitis, benign and malignant disease of the anorectum

Call for patient appointments: (314) 454-7177

Meet Dr. Wise. 

Dr. Paul Wise is a colorectal surgeon specializing in comprehensive colon and rectal cancer care. 

He has expertise in Crohn’s disease, ulcerative colitis, fissures, fistulae, intestinal stomas, and pelvic floor disorders. 

Dr. Wise earned his medical degree from Johns Hopkins University School of Medicine. He completed general surgery residency at Vanderbilt University Medical Center and a colon and rectal surgery fellowship at WashU Medicine.  

“Cancer care has improved in the past few decades, offering the same major operations using minimally invasive procedures, whether robotically, or laparoscopically. This helps patients recover more quickly. We want patients to get the best care, and Siteman offers them a multidisciplinary approach from world-renowned specialists who will ensure they receive the best care and outcomes available.” 

Dr. Wise

Degrees

Medical Degree
Johns Hopkins University School of Medicine, Baltimore, MD 
1996

Residency

Categorical Residency in General Surgery
Vanderbilt University Medical Center, Nashville, TN 
2003

Research Residency
Division of Hepatobiliary Surgery and Liver Transplantation 
Vanderbilt University Medical Center, Nashville, TN 
2001

Fellowship

Colon and Rectal Surgery Fellowship
WashU Medicine, St. Louis, MO 
2004

Research interests

Inherited colorectal cancer and hereditary colorectal cancer syndromes (Lynch syndrome, hereditary nonpolyposis colorectal cancer (HNPCC), familial adenomatous polyposis (FAP), polyposis syndromes), colon cancer, rectal cancer, anal cancer, colon and rectal polyps, inflammatory bowel disease (Crohn’s disease and ulcerative colitis), other disease of the colon and rectum (diverticulitis, benign and malignant disease of the anorectum) 

View research profile

Locations

Siteman Cancer Center
4500 Forest Park Avenue 
St. Louis, MO 63108 
Floor: 5th 
314-454-7177 
888-425-7946 
Appointments: 314-454-7177

Barnes-Jewish West County Hospital
Medical Office Building 4
1044 North Mason Road
Creve Coeur, MO 63141
Phone: 314-454-7177

Hospital affiliations

Barnes-Jewish Hospital 

Barnes-Jewish West County Hospital 

Board certifications

  • American Board of Surgery 
  • American Board of Colon and Rectal Surgery 

Dr. Wise in the news

More information

Professional memberships: 

  • American College of Surgeons 
  • American Society of Colon and Rectal Surgeons 
  • Southern Surgical Association 
  • Association for Surgical Education 
  • Association of Program Directors in Surgery 
  • CGA 
  • InSiGHT 
  • Chron’s & Colitis Foundation 
  • Western Surgical Assocation 
  • Piedmont Society of Colon and Rectal Surgery 

Awards and Honors: 

  • Alpha Omega Alpha Faculty election, Washington University Chapter 
  • Election to the Southern Surgical Association 
  • Inaugural fellow in the Washington University School of Medicine Academy of Educators 
  • 2019 Clinical Teacher of the Year Award 
  • Distinguished Service Teaching Awards, Washington University School of Medicine Class of 2020 
  • Chair, ASCRS Website Committee 
  • Fellow of the American College of Surgeons 
  • Fellow of the American Society of Colon and Rectal Surgeons 
  • Co-Editor, Washington Manual of Surgery