The maze procedure is a surgical treatment for atrial fibrillation, a common and potentially serious heart rhythm disorder.
Atrial fibrillation (sometimes called AFib) is an abnormal heartbeat rhythm. AFib can lead to serious complications, including heart failure and strokes.
The maze procedure creates a “maze” of scar tissue in the heart to block abnormal electrical signals.
Learn more about the maze procedure, including its definition, indications, candidate criteria, the surgical process, post-operative care, and potential risks and complications.
Cardiac surgeons at WashU Medicine

Heart surgeons at WashU Medicine see patients at Barnes-Jewish Hospital, one of the top hospitals in the nation for heart and vascular care, as well as convenient locations across the region.
What is the maze procedure?
The maze procedure (also called the Cox-Maze IV) is a surgical intervention designed to treat atrial fibrillation by creating a series of precise scar tissue lines in the upper chambers of the heart. This “maze” pattern of scar tissue disrupts the abnormal signals that cause AFib.
These scar lines, which resemble a maze, direct the electrical impulses to follow a controlled path, thereby restoring normal heart rhythm.
The procedure can be performed through traditional open-heart surgery (the “cut-and-sew” technique) or with less invasive approaches using radiofrequency, cryoablation, or other energy sources.
Did you know?
Experts at WashU Medicine developed the original Cox-Maze procedure in the 1980s. More recently, our surgeons have refined the surgery to its current version, the Cox-Maze IV. This means that when you see a cardiac surgeon at WashU Medicine, you’re working with the team that pioneered surgical treatment for AFib from the very beginning.
Read more about the legacy of heart & vascular care at WashU Medicine>>
Who might need a maze procedure?
The maze procedure is considered the gold standard for the treatment of atrial fibrillation.
People who may benefit from a maze procedure for AFib may have:
- Medication resistance: AFib that does not respond adequately to antiarrhythmic medications.
- Catheter ablation failure: Recurrence of AFib after attempts with less invasive catheter ablation procedures.
- Severe symptoms: Persistent symptoms such as palpitations, fatigue, shortness of breath, and decreased exercise tolerance affecting the quality of life.
- Risk of complications: High risk of thromboembolic events (including stroke) due to prolonged AFib.
- Planned surgery: Patients undergoing other cardiac surgeries (valve repair or replacement, coronary artery bypass grafting) who also have AFib may benefit from combining the maze procedure with the scheduled operation.
Who is a candidate for the maze procedure?
Before deciding to have a maze procedure for atrial fibrillation, your doctor will help you determine if you are a good candidate. This might include:
- Severity of AFib: Assessment of the frequency, duration, and symptoms of AFib episodes.
- Response to prior treatments: Evaluation of previous treatments and their effectiveness (including medications, cardioversion, catheter ablation).
- Overall health: Candidates should be in good general health and free from conditions that would contraindicate surgery.
- Other cardiac conditions: Patients with significant valvular disease, coronary artery disease, or other structural heart issues may benefit from the procedure.
Before having surgery, your health care provider may conduct certain tests, which may include:
- Physical examination: Comprehensive examination to assess cardiovascular health and eligibility for surgery.
- Imaging tests: Echocardiogram, CT scan, or MRI to evaluate the size and function of the atria and other heart structures.
- Electrocardiogram (ECG): To document and analyze the nature of AFib episodes.
- Holter monitor: Continuous ECG monitoring over 24-48 hours to detect and record AFib episodes.
- Stress test: To evaluate the heart’s response to physical exertion, especially in patients with concurrent coronary artery disease.
The maze procedure process
The maze procedure is a complex surgery to treat atrial fibrillation. Your health care team will help you understand the procedure and what to expect. In general, surgicl steps for the maze procedure may include:
- Anesthesia: General anesthesia is administered to ensure the patient is fully asleep and pain-free during the procedure.
- Accessing the heart: Depending on the technique, the heart is accessed through an open chest (sternotomy) or minimally invasive incisions.
- Creating the maze:
- Cut-and-sew technique: In traditional open-heart surgery, the surgeon makes precise incisions in the atrial tissue and then sutures them to create scar lines, forming the “maze.”
- Ablation techniques: In less invasive approaches, the surgeon uses radiofrequency energy, cryoablation (freezing), or other technologies to create the scar lines.
- Additional procedures: If necessary, addressing other cardiac conditions such as valve repair or coronary artery bypass grafting.
- Closure: The incisions are sutured, and the chest is closed.
The procedure duration varies depending on complexity and whether additional surgeries are performed concurrently. The surgery may typically range from 3 to 5 hours.
Post-operative care and recovery
Immediate postoperative care
- Monitoring: Close monitoring in an intensive care unit (ICU) immediately after surgery to ensure hemodynamic stability and detect any complications.
- Pain management: Administration of pain relief medications to ensure comfort during the initial recovery period.
- Wound care: Instructions on keeping the surgical site clean and preventing infection.
Recovery at home
- Activity restrictions: Gradual return to daily activities while avoiding strenuous exercise and heavy lifting for several weeks.
- Follow-up appointments: Regular check-ups with the surgical and cardiology team to monitor recovery, adjust medications, and address any complications.
Long-term care
- Antiarrhythmic medications: Initially, medications may be continued to support normal rhythm during the healing process, with potential tapering over time.
- Anticoagulation therapy: Medications to prevent blood clots, especially important in the immediate post-operative period and evaluated over the long term.
- Lifestyle changes: Heart-healthy diet, regular physical activity, smoking cessation, and stress management to support overall cardiovascular health.
Potential risks and complications
Surgical risks
- Infection: Risk of infection at the surgical site or within the chest.
- Bleeding: Risk of excessive bleeding during and after surgery.
- Stroke: Risk of stroke during or after the procedure.
- Heart block: Damage to the conduction system requiring a pacemaker.
- Atrial flutter: Potential for developing atrial flutter, a different type of arrhythmia that may require additional treatment.
Long-term considerations
- Recurrence of AFib: Some patients may experience a return of AF over time, possibly requiring additional treatments.
- Medication management: Ongoing assessment to determine the need for long-term antiarrhythmic or anticoagulant medications.
- Scar tissue formation: Monitoring for potential issues related to scar tissue in the heart that could affect rhythm.
Impact on quality of life
- Symptom relief: Significant improvement in symptoms such as palpitations, fatigue, and shortness of breath post-procedure.
- Emotional well-being: Addressing anxiety or depression related to living with AF and undergoing surgery.
- Functional capacity: Enhanced ability to engage in physical activities and improved overall quality of life.
The maze procedure is an effective surgical treatment for atrial fibrillation, offering significant symptom relief and improved heart rhythm control for many patients. Understanding the indications, surgical process, and potential risks and complications is essential for making informed decisions. If you or a loved one are considering the maze procedure, consulting with a specialized cardiac surgical team will help develop a personalized care plan tailored to your specific needs and circumstances.
