Matthew Silviera, MD, MS

Assistant Professor of Surgery

Expertise


Specialty Areas


  • Colon Cancer
  • Rectal cancer – neoadjuvant therapy, surgery and non-operative management
  • Anal cancer
  • Colon polyps
  • Diverticulitis
  • Ulcerative colitis and Crohn’s disease
  • Anorectal diseases – Hemorrhoids, Fissures, Abscess, Fistula, Condyloma, Pilonidal cysts
  • Inherited colorectal cancer and hereditary colorectal cancer syndromes
  • Intestinal stomas
  • Rectal prolapse
  • Constipation
  • Fecal incontinence

Common Procedures


  • Surgeries for rectal cancer
  • Diverticulitis
  • Ulcerative colitis
  • Crohn’s disease
  • Anorectal procedures
  • Creation and removal intestinal stomas
  • Laparoscopic procedures
  • Transanal endoscopic microsurgery
  • Robotic
  • Colonoscopy
  • Hemorrhoidectomy

Common Diagnoses Treated


  • Colon Cancer
  • Rectal cancer – neoadjuvant therapy, surgery and non-operative management
  • Anal cancer
  • Colon polyps
  • Diverticulitis
  • Ulcerative colitis and Crohn’s disease
  • Anorectal diseases – Hemorrhoids, Fissures, Abscess, Fistula, Condyloma, Pilonidal cysts
  • Inherited colorectal cancer and hereditary colorectal cancer syndromes
  • Intestinal stomas
  • Rectal prolapse
  • Constipation
  • Fecal incontinence
Education


Board Certifications


American Board of Surgery

American Board of Colon and Rectal Surgery

Degrees


Medical School: Temple University School of Medicine, Philadelphia, PA, 2005

Graduate School: Clinical Research and Transitional Medicine, Temple University, Philadelphia, PA, 2010

Residency


2012 General Surgery Residency, Temple University Hospital, Philadelphia, PA

Fellowship


2013 Colon and Rectal Surgery Fellowship, Washington University School of Medicine, St. Louis, MO

Professional Memberships


American College of Surgeons

American Society of Colon and Rectal Surgeons

Society of American Gastrointestinal and Endoscopic Surgeons

Awards and Honors


1992 Magna Cum Laude, The Pennsylvania State University, Hanover, NH

Research


Areas of Research Interest


Inflammatory bowel disease (IBD)

Colorectal cancer

Patient Outcomes

Enhanced Recovery after Surgery

Rectal cancer

Cost reduction of care for colon cancer

Clinical Trials


  1. “How well does pre-operative biopsy correlate with pathology after transanal endoscopic microscurgey (TEMS)”
    (Short Title: Pre-operative biopsy and TEMS)
  2. “A phase II multicenter randomized trial evaluating 3-year disease-free survival …”
    (Short Title: NOM)
  3. “A phase III, randomized, double blind, parallel group, placebo controlled, international, multicentre study to assess efficacy and safety of Cx601, adult allogeneic expanded adipose-derived stem cells (eASC), for the treatment of complex perianal fistula(s) in patients with Crohn’s disease over a period of 24 weeks and a follow-up period up to 52 weeks.”
    (Short Title: ADMIRE-CD II CX601-0303)
  4. “Washington University Inherited Colorectal Cancer and Polyposis Registry”
    (Short Title: ICCP Registry)
  5. “A Phase 1b, Multicenter, Randomized, Blinded, Placebo-controlled Study to Evaluate the Efficacy of Guselkumab in Subjects with Familial Adenomatous Polyposis”
    (Short Title: Janssen – CNTO1959COR1001)
  6. “Preoperative Evaluation, Clinicopathologic Factors, Management Strategies, and Outcomes of Colon and Rectal Cancer: A Multi-Institutional Experience”
    (Short Title: Colorectal Cancer Multi-Institute)
  7. “A Multi-Center Prospective Comparison of Intracorporeal and Extracorporeal Anastomoses for Minimally Invasive Right Colectomy”
    (Short Title: Prospective Right Colectomy)
  8. “Pilot study of ultrasound and Photoacoustic Imaging of Colon and Rectal Tumor Tissue”
    (Short Title: Photoacoustic colon imaging)
  9. “Short versus long interval to loop ileostomy reversal after ileal pouch surgery in patients with ulcerative colitis”
    (Short Title: SLIRPS Trial)
  10. “Ileal Pouch after Liver Transplant (I-PALT) Multicenter Study”
    (Short Title: I-PALT)
  11. “Novel Assessment of the Role of Surgery in Recurrent Diverticulitis: A Prospective, Observational Study of Observation versus Surgery in Recurrent Diverticulitis”
    (Short Title: NARSID)
  12. “A Phase 1b, Multicenter, Randomized, Blinded, Placebo-controlled Study to Evaluate the Efficacy of Guselkumab in Subjects with Familial Adenomatous Polyposis”
    (Short Title: Janssen – CNTO1959COR1001)
  13. “A phase 2, multicenter, randomized, double-blind, placebo-controlled study of naldemedine in patients undergoing surgeries that include a bowel resection or bowel transection”
    (Short Title: Shionogi)
  14. “Transdisciplinary Team Science in Colorectal Cancer Prognosis: The ColoCare Study”

Innovations


Non-operative management of colorectal cancer

Publications

Locations


Hospital Affiliations


Barnes-Jewish Hospital

Barnes-Jewish West County Hospital

Patients Seen At


Center for Advanced Medicine
4921 Parkview Place, Suite 8C – GI Center
St. Louis, MO 63110
Telephone: 314-454-7177
Fax: 888-425-7946

Barnes-Jewish West County Hospital
1040 North Mason Rd
Medical Office Building 1, Suite 120
St. Louis, MO 63141
Telephone: 314-454-7177
Fax: 888-425-7946

News and Stories
Contact


To request an appointment with Dr. Silviera, please call (314) 454-7177 or request an appointment online.