Steven R. Hunt, MD

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• Colon Cancer
• Rectal cancer – neoadjuvant therapy, surgery and non-operative management
• Anal cancer
• Colon polyps
• Diverticulitis
• Ulcerative colitis and Crohn’s disease
• Anorectal diseases – Hemorrhoids, Fissures, Abscess, Fistula, Condyloma, Pilonidal cysts
• Inherited colorectal cancer and hereditary colorectal cancer syndromes
• Intestinal stomas
• Rectal prolapse
• Constipation
• Fecal incontinence

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• Surgeries for rectal cancer
• Diverticulitis
• Ulcerative colitis
• Crohn’s disease
• Anorectal procedures
• Creation and removal intestinal stomas
• Laparoscopic procedures
• Transanal endoscopic microsurgery
• Robotic
• Colonoscopy
• Hemorrhoidectomy

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• Colon Cancer
• Rectal cancer – neoadjuvant therapy, surgery and non-operative management
• Anal cancer
• Colon polyps
• Diverticulitis
• Ulcerative colitis and Crohn’s disease
• Hemorrhoids
• Fissures
• Abscesses
• Fistula
• Condyloma
• Pilonidal cysts
• Inherited colorectal cancer and hereditary colorectal cancer syndromes
• Intestinal stomas
• Rectal prolapse
• Constipation
• Fecal incontinence

Board Certifications

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American Board of Surgery

American Board of Colon and Rectal Surgery

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Inflammatory Bowel Disease (IBD)

Ulcerative colitis

Crohn’s disease

Colorectal cancer

Rectal Cancer

Patient Outcomes

Enhanced Recover after Surgery

Cost reduction of care for colon cancer

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1. “How well does pre-operative biopsy correlate with pathology after transanal endoscopic microscurgey (TEMS)”
   (Short Title: Pre-operative biopsy and TEMS)
2. “A phase II multicenter randomized trial evaluating 3-year disease-free survival …”
   (Short Title: NOM)
3. “A phase III, randomized, double blind, parallel group, placebo controlled, international, multicentre study to assess efficacy and safety of Cx601, adult allogeneic expanded adipose-derived stem cells (eASC), for the treatment of complex perianal fistula(s) in patients with Crohn’s disease over a period of 24 weeks and a follow-up period up to 52 weeks.”
   (Short Title: ADMIRE-CD II CX601-0303)
4. “Washington University Inherited Colorectal Cancer and Polyposis Registry”
   (Short Title: ICCP Registry)
5. “A Phase 1b, Multicenter, Randomized, Blinded, Placebo-controlled Study to Evaluate the Efficacy of Guselkumab in Subjects with Familial Adenomatous Polyposis”
   (Short Title: Janssen – CNTO1959COR1001)
6. “Preoperative Evaluation, Clinicopathologic Factors, Management Strategies, and Outcomes of Colon and Rectal Cancer: A Multi-Institutional Experience”
   (Short Title: Colorectal Cancer Multi-Institute)
7. “A Multi-Center Prospective Comparison of Intracorporeal and Extracorporeal Anastomoses for Minimally Invasive Right Colectomy”
   (Short Title: Prospective Right Colectomy)
8. “Pilot study of ultrasound and Photoacoustic Imaging of Colon and Rectal Tumor Tissue”
   (Short Title: Photoacoustic colon imaging)
9. “Short versus long interval to loop ileostomy reversal after ileal pouch surgery in patients with ulcerative colitis”
   (Short Title: SLIRPS Trial)
10. “Ileal Pouch after Liver Transplant (I-PALT) Multicenter Study”
    (Short Title: I-PALT)
11. “Novel Assessment of the Role of Surgery in Recurrent Diverticulitis: A Prospective, Observational Study of Observation versus Surgery in Recurrent Diverticulitis”
    (Short Title: NARSID)
12. “A Phase 1b, Multicenter, Randomized, Blinded, Placebo-controlled Study to Evaluate the Efficacy of Guselkumab in Subjects with Familial Adenomatous Polyposis”
    (Short Title: Janssen – CNTO1959COR1001)
13. “A phase 2, multicenter, randomized, double-blind, placebo-controlled study of naldemedine in patients undergoing surgeries that include a bowel resection or bowel transection”
    (Short Title: Shionogi)
14. “Transdisciplinary Team Science in Colorectal Cancer Prognosis: The ColoCare Study”

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Non-operative management of colorectal cancer

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Eswara JR, Raup VT, Potretzke AM, Hunt SR, Brandes SB.  Outcomes of latrogenic genitourinary injuries during colorectal surgery.  Urology. 2015 Dec;86(6):1228-1233.  doi:10.1016/j.urology.2015.06.065. Epub 2015 Sep 12.

Garcia-Aguilar J, Chow OS, Smith DD, Marcet JE, Cataldo PA, Varma MG, Kumar AS, Oommen S, Coutsoftides T, Hunt SR, Stamos MJ, Ternent CA, Herzig DO, Fichera A, Polite BN, Dietz DW, Patil S, Avila K.  Effect of adding m Folfox6 after neoadjuvant chemoradiation in locally advanced rectal cancer: a multicentre, phase 2 trial.  Timing of Rectal Cancer Response to Chemoradiation Consortium.  Lancet Oncol. 2015 Aug;16(8):957-966. doi: 10.1016/S1470-2045(15)00004-2. Epub 2015 Jul 14.

Hawkins AT, Hunt SR.  Watch and Wait:  Is Surgery Always Necessary for Rectal Cancer? Curr Treat Options in Oncol.  2016 17(5):1-22.

Klos CL, Safar B, Wise PE, Hunt SR, Mutch MG, Birnbaum EH, Fleshman JW, Dharmarajan S.  Impaired outcome colitis-associated rectal cancer versus sporadic cancer. J Surg Res. 2016 Jul;204(1):123-9, PMID 27451878.

Khwaja SS, Roy A, Markovina S, Dewees TA, Hunt SR, Tan B, Myerson RJ, Olsen JR, Parikh PJ.  Quality of life outcomes from a phase 2 trial of short course radiation therapy followed by Folfox chemotherapy as preoperative treatment for rectal cancer.  Int J Radiat Oncol Biol Phys. 2016 Aug 1;95(5):1429-1438. Doi: 10.1016/j.ijrobp.2016.03.020. Epub 2016 Mar 25.

Hawkins AT, Wells KO, Krishnamurty DM, Hunt SR, Mutch MG, Wise PE, Silviera ML.  Preoperative chemotherapy and survival for large anorectal gastrointestinal stromal tumors:  a national analysis of 333 cases.  Ann Surg Oncol, 2017 May;24(5);1195-1201. DOI:   10.1245/S10434-016-5706-1. Epub 2017 Jan 3. PMID:28050726.

Wells KO, Hawkins AT, Krishnamurthy DM, Dharmarajan S, Glasgow SC, Hunt SR, Mutch MG, Wise PE, Silviera ML.  Omission of adjuvant chemotherapy is associated with increased mortality in patients with T3N0 colon cancer with inadequate lymph node harvest.  Dis Colon rectum, 2017 Jan;60(1):15-21.

Roy A, Mahasittiwat P, Weiner AA, Hunt SR, Mutch MG, Birnbaum EH, Kodner IJ, Read TE, Fleshman JW, Olsen JR, Myerson RJ, Parikh PJ.  Preoperative short-course radiation therapy for rectal cancer provides excellent disease control and toxicity:  results from a single US institution.  Pract Radiat Oncol.  2017 Jan-Feb;7(1)e51-e58.  Doi:10.1016/j.prro.2016.08.010. Epub 2016 Aug 31.

Markovina S, Youssef F, Roy A, Aggarwal S, Khwaja S, DeWees T, Tan B, Hunt S, Myerson RJ, Chang DT, Parikh PJ, Olsen JR.  Improved Metastasis and Disease Free Survival with Preoperative Sequential Short Course Radiation Therapy and FOLFOX Chemotherapy for Rectal Cancer Compared with Neoadjuvant Long Course Chemoradiotherapy:  Results of a Matched Pair Analysis.  Int J Radiat Oncol Biol Phys. 2017 Oct 1;99(2):417-426. doi: 10.1016/j.ijrobp.2017.05.048. Epub 2017 Jun 6. 

Ohman KA, Wan L, Guthrie T, Johnston B, Leinicke JA, Glasgow SC, Hunt SR, Mutch MG, Wise PE, Silviera ML. Combination of Oral Antibiotics and Mechanical Bowel Preparation Reduces Surgical Site Infection in Colorectal Surgery. J Am Coll Surg. 2017 Oct;225(4):465-471.

Mullen MM, Kuroki LM, Hunt SR, Ratkowski KL, Mutch DG.  A transperineal approach to hysterectomy of a retained didelphic uterine horn.  Obstet Gynecol.  2017 Sep;130(3):561-64.  doi: 10.1097/AOG.0000000002196.

Mukkai Krishnamurthy D and Hawkins AT*, Wells KO, Mutch MG, Glasgow S, Hunt SR, Dharmarajan S.  Neoadjuvant Radiation Therapy Is Associated with Improved Survival in Locally  Advanced Colon Cancer: A Cohort Analysis. Journal of Gastrointestinal Surgery.  2018 Feb 9. doi: 10.1007/s11605-018-3676-2. [Epub ahead of print] PMID: 29427227.

Benson AB 3^rd, Venook AP, Al-Hawary MM, Cederquist L, Chen YJ, Ciombor KK, Cohen S, Cooper HS, Deming D, Engstrom PF, Garrido-Laguna I, Gem JL, Grothey A, Hochster HS, Hoffe S, Hunt SR, kamel A, Kirilcuk N, Krishnamurthi S, Messersmith WA, Meyerhardt J, Miller ED, Mulcahy MF, Murphy JD, Nurkin S, Saltz L, Sharma S, Shibata D, Skibber JM, Sofocleous CT, Stoffel EM, Stotsky-Himelfarb E, Willett CG, Wuthrick E, Gregory KM, Freedman-Cass DA.  NCCN Guidelines Insights:  Colon Cancer, Version 2.2018.  J Natl Compr Canc Netw.  2018 Apr;16(4):359-369. doi: 10.6004/jnccn.2018.0021.

Chapman WC Jr., Choi P, Hawkins AT, Hunt SR, Silviera ML, Wise PE, Mutch MG, Glasgow SC. Benchmarking rectal cancer care: institutional compliance with a longitudinal checklist. J Surg Res. 2018 May;225:142-147.

Krishnamurty DM, Hawkins AT, Wells KO, Mutch MG, Silviera ML, Glasgow SC, Hunt SR, Dharmarajan S.  Neoadjuvant Radiation Therapy in Locally Advanced Colon Cancer:  a Cohort Analysis.  J Gastrointest Surg. 2018 May;22(5):906-912. doi: 10.1007/s11605-018-3676-2.   Epub 2018 Feb 9.

Geltzeiler CB, Birnbaum EH, Silviera ML, Mutch MG, Vetter J, Wise PE, Hunt SR, Glasgow SC. Combined rectopexy and sacrocolpopexy is safe for correction of pelvic organ prolapse.  Int J Colorectal Dis. 2018 Oct;33(10):1453-1459.

Marco MR, Zhou L, Patil S, Marcet JE, Varma MG, Oommen S, Cataldo PA, Hunt SR, Kumar A, Herzig DO, Fichera A, Polite BN, Hyman NH, Ternent CA, Stamos MJ, Pigazzi A, Dietz D, Yakunina Y, Pelossof R, Garcia-Aguilar J.  Consolidation mFOLFOX6 Chemotherapy after Chemoradiotherapy Improves Survival in Patients with Locally Advanced Rectal Cancer:  FinalResults of a Multicenter Phase II Trial.  Timing of Rectal Cancer Response to Chemoradiation Consortium.  Dis Colon Rectum. 2018 Oct;61(10):1146-1155. doi: 10.1097/DCR.0000000000001207

Rosen DR, Wolfe RC, Damle A, Atallah C, Chapman WC Jr, Vetter JM, Mutch MG, Hunt SR, Glasgow SC, Wise PE, Smith RK, Silviera ML.  Thoracic Epidural Analgesia: Does It Enhance Recovery?  Dis Colon Rectum. 2018 Dec;61(12):1403-1409.

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Barnes-Jewish Hospital

Patients Seen At

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Siteman Cancer Center at 4500 Forest Park Avenue
4500 Forest Park Avenue
St. Louis, MO 63108
Floor: 5th

Center for Advanced Medicine- South County
5201 Midamerica Plaza, Suite 2300
St. Louis, MO 63129
Telephone: 314-454-7177
Fax: 888-425-7946

Siteman Cancer Center- South County
5225 Midamerica Plaza
St. Louis, MO 63129
Telephone: 314-454-7177
Fax: 888-425-7946