Peripheral vascular disease is a common circulatory problem where narrowed blood vessels reduce blood flow to the limbs, especially to the legs.

Peripheral vascular disease (sometimes called PVD) generally happens when arteries are narrowed due to a buildup of fatty deposits, a condition known as atherosclerosis.

If you have peripheral vascular disease, you may experience limited blood flow to your limbs, causing discomfort or pain, particularly when walking. Early diagnosis and management are crucial for preventing serious complications.

Vascular surgeons at WashU Medicine

Vascular surgeons at WashU Medicine see patients at Barnes-Jewish Hospital, one of the top hospitals in the nation for heart and vascular care, as well as convenient locations across the St. Louis area. Our team has the experience to treat even the rarest and most complex cases.

Risk factors

Several factors can increase your risk of developing peripheral vascular disease, including:

  • Smoking: Smoking damages the blood vessels and accelerates the development of atherosclerosis.
  • Diabetes: High blood sugar levels can damage blood vessels and increase the risk of atherosclerosis.
  • High blood pressure: Hypertension can harm the artery walls, making them prone to atherosclerosis.
  • High cholesterol: Excess cholesterol can accumulate on artery walls and restrict blood flow.
  • Family history of vascular disease: Genetic factors can increase your susceptibility to PVD.
  • Obesity: Excess body weight increases the risk of other conditions that contribute to peripheral vascular disease, such as diabetes and hypertension.
  • Sedentary lifestyle: Lack of physical activity can contribute to the development of conditions that increase the risk of peripheral vascular disease.

Causes

The primary cause of peripheral vascular disease is atherosclerosis, where plaque builds up on the walls of your arteries.

Other causes can include inflammation of the blood vessels, injury to limbs, unusual anatomy of muscles or ligaments, and exposure to radiation.

Screenings and diagnosis

To diagnose peripheral vascular disease, your doctor may conduct a variety of tests, including:

  • Ankle-brachial index (ABI): This compares the blood pressure in your ankle with the blood pressure in your arm.
  • Ultrasound: This test is used to detect blockages in your veins or arteries.
  • Angiography: This test is used to view blood flow through the arteries.
  • Blood tests: This test is used to check for conditions related to PVD.

Symptoms

Peripheral vascular disease often causes symptoms like:

  • Painful cramping in the hip, thigh, or calf muscles after activity (claudication)
  • Leg numbness or weakness
  • Coldness in your lower leg or foot
  • Sores on your toes, feet, or legs that won’t heal

Treatment

Treatment for peripheral vascular disease includes lifestyle changes, medications, and possibly surgical procedures.

Medications

Your doctor may prescribe medications to:

  • Lower cholesterol (statins)
  • Control high blood pressure
  • Manage diabetes
  • Prevent blood clots (antiplatelet medications)

Surgical care and procedures

In more severe cases, procedures such as angioplasty, where a balloon is inflated within the artery to open it, or bypass surgery, which redirects blood flow around the blocked artery, may be necessary.

Lifestyle changes

Making healthy lifestyle choices plays a pivotal role in the management and prevention of peripheral vascular disease.

Healthy lifestyle choices for vascular health include:

  • Quit smoking
  • Exercise regularly
  • Maintain a healthy diet
  • Keep diabetes under control
  • Regularly monitor your blood pressure and cholesterol levels

Potential complications

If peripheral vascular disease is not properly treated, it can lead to serious complications such as:

  • Critical limb ischemia: Severe blockage can reduce blood flow and lead to wounds that don’t heal, infections, and in extreme cases, amputation.
  • Heart attack or stroke: Due to the same factors that cause peripheral vascular disease, such as atherosclerosis, you may be at a higher risk.

Recovery and rehabilitation

After a procedure for peripheral vascular disease, follow your doctor’s recommendations closely to ensure proper healing and prevent complications.

This may involve:

  • Taking prescribed medications
  • Participating in a supervised exercise program
  • Regular follow-up appointments

By understanding peripheral vascular disease, recognizing its risk factors, symptoms, and seeking appropriate treatment, you can manage this condition effectively and maintain a healthy and active lifestyle.