Lewis J Thomas IV, MD

Assistant Professor of Surgery


Specialty Areas

Urologic oncology, bladder cancer, prostate cancer, kidney cancer, testis cancer

Common Diagnoses Treated

Urologic oncology

Bladder cancer

Prostate cancer

Kidney cancer

Testis cancer



Medical School: University of Missouri School of Medicine, Columbia, MO 2012


2012-2018 Urology Residency, University of Iowa Hospitals and Clinic, Iowa City, IA


2018-2020 Urologic Oncology Fellowship, Cleveland Clinic, Glickman Urologic and Kidney Institute, Cleveland, OH

Professional Memberships

American Urologic Society

Iowa Urologic Society

Society of Urologic Oncology


Areas of Research Interest

Bladder and prostate cancer


Steinberg RL, Thomas LJ, Brooks N, Mott SL, Vitale A, Crump T, Rao MY, Daniels MJ, Wang J, Nagaraju S, DeWolf WC, Lamm DL, Kates M, Hyndman ME, Kamat AM, Bivalacqua TJ, Nepple KG, O’Donnell MA. Multi-Institution Evaluation of Sequential Gemcitabine and Docetaxel as Rescue Therapy for Nonmuscle Invasive Bladder Cancer. J Urol. 2020 May;203(5):902-909. doi: 10.1097/JU.0000000000000688. Epub 2019 Dec 10. PMID: 31821066.

Zhang JH, Ericson KJ, Thomas LJ, Knorr J, Khanna A, Crane A, Mittal R, Zampini A, Fascelli M, Murthy PB, Haber GP, Lee B. Large Single Institution Comparison of Perioperative Outcomes and Complications of Open Radical Cystectomy, Intracorporeal Robot-Assisted Radical Cystectomy and Robotic Extracorporeal Approach. J Urol. 2020 Mar;203(3):512-521. doi: 10.1097/JU.0000000000000570. Epub 2019 Oct 3. PMID: 31580189.

Thomas L, Baratchian M, Sharifi N. Supraphysiologic Testosterone Solutions for Enzalutamide-resistant Prostate Cancer. Eur Urol. 2020 Feb;77(2):156-157. doi: 10.1016/j.eururo.2019.07.037. Epub 2019 Jul 31. PMID: 31377027.

Boi SK, Orlandella RM, Gibson JT, Turbitt WJ, Wald G, Thomas LJ, Norris KE, Bing, M, Bertrand L, Gross BP, Makkouk A, Starenki D, Sorge RE, Weiner GJ, Salem AK, Lubaroff DM, Arend RC, Nandagopal L, Li P, Brown JA, Yang E, Nepple KG, Marquez-Lago TT, Norian LA. “Obesity Reduces Response Rates to PD-1-based Checkpoint Blockade Therapeutics in Renal Cancer. Science Translational Medicine (Submitted)

Thomas LJ, Brooks MA, Stephenson AJ. The Role of Imaging in the Diagnosis, Staging, Response to Treatment, and Surveillance of Patients with Germ Cell Tumors of the Testis. Urol Clin North Am. 2019 Aug;46(3):315-331. doi: 10.1016/j.ucl.2019.05.001. PMID: 31277727.

Steinberg RL, Thomas LJ, Bell SL, O’Donnell MA. “Multi-Perspective Tolerance Evaluation of BCG with Interferon in the Treatment of Non-Muscle Invasive Bladder Cancer.” Bladder Cancer, 5(1) Jan 2019.

Steinberg RL, Thomas LJ, O’Donnell MA. “Combination Intravesical Chemotherapy for Non-Muscle Invasive Bladder Cancer.” European Urology Focus. S2405-4569 (18). 2018

Thomas LJ, Steinberg RL, O’Donnell MA. “Combination Intravesical Chemotherapy for Non-Muscle Invasive Bladder Cancer – Beyond the Abstract.” UroToday/GU-OncToday. July, 2018

Bertrand LA, Thomas LJ, Li P, Buchta CM, Boi SK, Orlandella RM, Brown JA, Nepple KG, Norian LA. “Obesity as Defined by Waist Circumference but not Body Mass Index is Associated with Higher Renal Mass Complexity.” Urologic Oncology. 35(11). 2017

Thomas LJ, Tracy CR. “Work-up and Treatment of Funguria” AUA Update Series

Steinberg RL, Velaer KN, Thomas LJ, O’Donnell MA, Nepple KG. “Quadruple Immunotherapy of Bacillus CalmetteGuérin, Interferon, Interleukin-2 and Granulocyte Macrophage Colony Stimulating Factor as Salvage Therapy for NonMuscle Invasive Bladder Cancer.” Urologic Oncology. 35(12) 2017

Steinberg RL, Brooks NA, Thomas LJ, Mott SL, O’Donnell MA. “Bacillus Calmette-Guérin (BCG) Strain Does not Affect Recurrence-free Survival when used Intravesically with Interferon-alpha2b for Non-muscle Invasive Bladder Cancer.” Urologic Oncology. 35(5) 2017

Velaer K, Steinberg RL, Thomas LJ, O’Donnell MA, Nepple KG. “Experience with Sequential Intravesical Gemcitabine and Docetaxel as Salvage Therapy for Non-Muscle Invasive Bladder Cancer.” Curr Urol Rep. 17(5). 1-5: 2016.

Steinberg RL, Thomas LJ, Mott S, O’Donnell MA. “Bacillus Calmette-Guérin (BCG) Treatment Failures with Non-Muscle Invasive Bladder Cancer: A Data-Driven Definition for BCG Unresponsive Disease.” Bladder Cancer. 2(2). 215-224: 2016.

Steinberg RL, Thomas LJ, Nepple KG. “Intravesical and Alternative Bladder Preservation Therapies in the Management of Non-Muscle Invasive Bladder Cancer Unresponsive to Bacillus Calmette-Guerin.” Urologic Oncology: Seminars and Original Investigations. 34. 279-289: 2016.

Thomas LJ, Tracy CR “Treatment of Fungal Urinary Tract Infection” The Urologic Clinics of North America. 42(4) 473- 483: 2015.

Steinberg RL, Thomas LJ, O’Donnell MA. “Bacillus Calmette-Guérin (BCG) Treatment Failures in Non-Muscle Invasive Bladder Cancer: What Truly Constitutes Unresponsive Disease.” Bladder Cancer. 1(2). 105-116: 2015.

Steinberg RL, Thomas LJ, O’Donnell MA, Nepple KG. “Sequential Intravesical Gemcitabine and Docetaxel for the Salvage Treatment of Non-Muscle Invasive Bladder Cancer.” Bladder Cancer. 1(1). 65-72: 2015.

Greenberg MB, Penn AA, Thomas LJ, El-Sayed YY, Caughey AB, Lyell DJ. “Neonatal Medical Admission in a Term and Late-Preterm Cohort Exposed to Magnesium Sulfate.” American Journal of Obstetrics and Gynecology. 204(6) e1-7: 2011.

Thomas LJ, Zweig AP, Tosh AK. “An Adolescent with Chronic Giardiasis Mimicking Anorexia Nervosa.” International Journal of Adolescent Medicine and Health. 26(2) 293-295: 2014.

Hughes MS, Marsh JN, Arbeit JM, Neumann RG, Fuhrhop RW, Wallace KD, Thomas LJ, Smith J, Agyem K, Lanza GM, Wickline SA. “Application of Renyi Entropy for Ultrasonic Molecular Imaging.” Journal of the Acoustical Society of America. May 2009.


Hospital Affiliations

Barnes-Jewish Hospital

Barnes-Jewish St. Peters Hospital

VA Medical Center – St. Louis – John Cochran Division

Patients Seen At

Center for Advanced Medicine
4921 Parkview Place
11th Floor, Suite C
St. Louis, MO 63110
Fax: 314-454-5244

Barnes-Jewish St. Peters Hospital
70 Jungermann Circle
Medical Office Building 2, Suite 402
St. Peters, MO 63376
Fax: 314-454-5244

VA Medical Center: John Cochran Division
915 North Grand Boulevard
St. Louis, MO 63106


To request an appointment with Dr. Thomas, please call (314) 362-8200.