Lijin Li, PhD

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• Cancer vaccines
• Immunology

Degrees

2005 PhD, Microbiology & Immunology
University of Arizona, Tucson, AZ

2010 Postgraduate Research Associate, Cancer Immunotherapy
Washington University School of Medicine, St. Louis, MO

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Awards and Honors

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People’s Scholarship (1988 and 1989)

Shanghai Medical University, Shanghai, China.

Outstanding Student Award (1990)

Shanghai Medical University, Shanghai, China.

Guanghua Scholarship (1993)

Shanghai Medical University, Shanghai, China.

Graduate Registration Scholarship (2001)

University of Arizona, Tucson, AZ.

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Preclinical development and clinical translation of cancer neoantigen vaccines, with a focus on the mRNA-LNP vaccine platform.

Publications

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Peng H, Li L (co-first author), Zuo C, Chen MY, Zhang X, Myers NB, Hogg GD, DeNardo DG, Goedegebuure SP, Hawkins WG, Gillanders WE. Combination TIGIT/PD-1 blockade enhances the efficacy of neoantigen vaccines in a model of pancreatic cancer. Front Immunol. 2022:13:1039226.

Li L, Zhang X, Wang X, Kim SW, Herndon JM, Becker-Hapak MK, Carreno BM, Myers NB, Sturmoski MA, McLellan MD, Miller CA, Johanns TM, Tan BR, Dunn GP, Fleming TP, Hansen TH, Goedegebuure SP, Gillanders WE. Optimized polyepitope neoantigen DNA vaccines elicit neoantigen-specific immune responses in preclinical models and in clinical translation. Genome Med. 2021:13(1):56.

Li L, Goedegebuure SP, Gillanders W. Cancer vaccines: shared tumor antigens return to the spotlight. Signal Transduct Target Ther. 2020:5(1):251.

Li L, Goedegebuure SP, Gillanders WE. Preclinical and clinical development of neoantigen vaccines. Ann Oncol. 2017:28(suppl_12):11-17.

Li L, Goedegebuure SP, Fleming TP, Gillanders WE. Developing a clinical development paradigm for translation of a mammaglobin-A DNA vaccine. Immunotherapy. 2015:7(7):709-711.

Li L, Kim S, Herndon JM, Goedegebuure P, Belt BA, Satpathy AT, Fleming TP, Hansen TH, Murphy KM, Gillanders WE. Cross-dressed CD8α+/CD103+ dendritic cells prime CD8+ T cells following vaccination. Proc Natl Acad Sci USA. 2012:109(31):12716-12721.

Li L, Goedegebuure P, Mardis ER, Ellis MJ, Zhang X., Herndon JM, Fleming TP, Carreno BM, Hansen TH, Gillanders WE. Cancer genome sequencing and its implications for personalized cancer vaccines. Cancers (Basel). 2011:3(4):4191-4211.