Mark H. Hoofnagle, MD, PhD
Assistant Professor of Surgery
Section of Acute and Critical Care Surgery
Division of General Surgery
- Phone: 314-362-5298
Specialties
- Trauma
- Emergency general surgery
- Surgical critical care
- Chest wall reconstruction
- Skin and soft tissue reconstruction
- General surgical procedures
- Rib and sternal fractures
- Traumatic injury from blunt and penetrating mechanisms
- Cholecystitis
- Appendicitis
- Necrotizing soft tissue infections
- Bowel obstruction
- Mesenteric ischemia
- Diverticulitis
- Chronic respiratory failure
- Feeding access
Call for patient appointments: 314-362-5298
Meet Dr. Hoofnagle
Dr. Mark Hoofnagle is a general surgeon specializing in emergency trauma surgery.
He has expertise in chest wall reconstruction, skin and soft tissue reconstruction, traumatic injury, necrotizing soft tissue infection, bowel obstruction, diverticulitis, cholecystitis, chronic respiratory failure, feeding access, and mesenteric ischemia.
Dr. Hoofnagle earned his medical degree from University of Virginia School of Medicine. He completed general surgery residency training at University of Maryland Medical Center and a surgical critical care and trauma, acute care, and emergency general surgery fellowship at University of Pennsylvania.
I study the effects of public policy on the gun violence epidemic, with a focus on the interactions between state laws and gun trafficking, as well as state policies on abortion restriction and maternal mortality.
Dr. Hoofnagle
Degrees
Medical Degree
University of Virginia School of Medicine, Charlottesville, VA
2009
Residency
General Surgery Residency
University of Maryland Medical Center, Baltimore MD, 2009-2016
Fellowship
Surgical Critical Care and Trauma, Acute Care, and Emergency General Surgery Fellowship
University of Pennsylvania, Philadelphia, PA
2016-2018
Research interests
Basic Science
Our ACCS lab studies the physiologic changes in the trauma patient and factors contributing to deep venous thrombosis, acute lung injury and sepsis. I study the interactions between the vasculature and the coagulation system that result in traumatically injured and critically-ill patients being more susceptible to blood clots and venous thromboembolism.
Clinical
As part of the ACCS division I perform research evaluating outcomes in trauma patients related to DVT prophylaxis, antibiotics use and transfusion. Research projects include evaluation of outcomes in COVID patients, DVT, surgical site infection, trauma resuscitation and mass transfusion, whole blood and traumatic brain injury.
Policy
I study the effects of public policy on the gun violence epidemic, with a focus on the interactions between state laws and gun trafficking, as well as state policies on abortion restriction and maternal mortality.
Locations
Barnes-Jewish Hospital
1 Barnes Jewish Hospital Plaza
St. Louis, MO 63110
Fax: 888-840-6225
Appointments: 314-273-7373
Hospital affiliations
Barnes-Jewish Hospital
Board certifications
- Surgical Critical Care
- General Surgery
Dr. Hoofnagle in the news
- “Without Roe v. Wade, U.S. Maternal Mortality Rates May Get Even Worse,” Time Magazine
- “Overturning Roe v. Wade Could Make Maternal Mortality Even Worse,” FiveThirtyEight
- “The Link Between America’s Rising Maternal Mortality Rates and Abortion,” Salon
- “The Hidden Side of Overturning Roe v. Wade,” Business Insider
- “Restrictive State Abortions Bans – A Reproductive Injustice,” The New England Journal of Medicine
- “WashU Surgeon Works to Reduce Gun Violence,” Fox2News St. Louis
- “Episode 168: Battling False Science: How Physicians Can Help Patients Discover the Truth with Dr. Mark Hoofnagle,” – Docworking: The Whole Physician Podcast
- “A Town Hall Discussion on Gun Violence,” West End Word
- “Clay’s Town Hall Meeting on Gun Violence Brings Outpouring of Emotion,” St. Louis Post-Dispatch
- “U.S. Rep Lacy Clay: We’ve Reached a Tipping Point on Gun Violence,” St. Louis Public Radio
- “How COVID-19 Can Lead To Amputation– And Other Potential Cardiovascular System Complications to Know,” Self
- “Gun Violence: St. Louis’ Other Public Health Crisis,” Department of Surgery News
Professional Memberships
American Association for the Advancement of Science (Member, 1995-present)
American College of Surgeons (Associate Fellow, 2009-2019, Fellow 2020 – present)
Society of Critical Care Medicine (Member, 2016 – present)
Eastern Association for the Surgery of Trauma (Member, 2017 – present)
American Association for the Surgery of Trauma (Associate Fellow 2019-2021, Fellow 2021 – present)
North American Vascular Biology Organization (Member, 2019 – present)
American Heart Association, Council on ATVB, Council on PVD (Member, 2019 – present)
Shock Society (Member 2019 – present)
Awards and Honors
Postdoctoral Awards
- Thurston R. Adams Prize for Research (2012, 2013)
- General Surgery Research Retreat Junior Resident Award (2013)
- Funding Awards
- 1T32CA154274-01 T32 Training Grant in Cancer biology (UMD) (2011-2013)
Graduate Funding Awards
- 5T32HL007284-28 T32 Cardiovascular Research Training Grant (UVA) (2003-2005)
- 2000-2002 2T32GM007267-22A1 Medical Scientist Training Program Grant (UVA) (2000-2002)
Undergraduate Awards
- Graduation Magna Cum Laude, Honors in Physics (1999)
- Inducted into Phi Beta Kappa National Honor Society (1999)
- Inducted into Sigma Pi Sigma, Physics National Honor Society (1999)
- Elected Bucknell University SGA congressman (1998)
- Elected to Bucknell University Appropriations Committee (1997)
- Elected to Bucknell University Judicial Board (1996)