A cholecystectomy is a surgical procedure designed to remove the gallbladder—a small organ located beneath the liver.
The gallbladder is a small organ that stores bile. It is located beneath the liver and is connected to the digestive system by ducts called the biliary tree.
Bile is a strong enzyme that helps the body break down fat. The liver produces bile, which is then stored in the gallbladder until it is used to break down fat into usable energy.
Cholecystectomy is typically performed to treat gallstones, cholecystitis (gallbladder inflammation), and other gallbladder-related diseases.
Gallbladder removal is common, and it is possible to live an ordinary life without your gallbladder. Some people may experience discomfort from eating certain foods after cholecystectomy, but your health care provider can help you learn about lifestyle changes for life without a gallbladder.
HPB-GI surgeons at WashU Medicine

Our surgeons perform a high volume of gallbladder removals with excellent outcomes. We have experts in all areas of gastrointestinal surgery, meaning we can help people with problems ranging from simple to the most complex of surgeries.
Who might need a cholecystectomy?
A person may need a cholecystectomy to address several gallbladder-related conditions that cause significant discomfort and health risks.
Common reasons for this surgery include:
- Gallstones, which can block bile flow and lead to severe pain or infection
- Cholecystitis, which is the inflammation of the gallbladder
- Gallbladder polyps, which might signify a risk of cancer
- Bile duct cancer, which affects the ducts carrying bile from the liver to the gallbladder
These conditions can result in intense symptoms like abdominal pain, nausea, fever, and jaundice.
Removing the gallbladder can help to eliminate these symptoms and restore normal function and health.
Learn more about gallbladder disease>>
Symptoms and diagnosis
Common symptoms signaling the need for a cholecystectomy include:
- Biliary colic: A sharp, intense pain, known as biliary colic, typically felt in the upper right or center of the abdomen, often worsening after eating.
- Nausea and vomiting: A frequent feeling of queasiness and the urge to vomit, which may lead to dehydration.
- Fever: Elevated body temperature signaling an infection or inflammation in the gallbladder.
- Jaundice: Yellowing of the skin and eyes due to the buildup of bilirubin, indicating possible bile duct obstruction.
Diagnosis involves a combination of medical imaging techniques, such as ultrasound, CT scans and MRIs, to determine the presence and severity of gallbladder conditions.
Screening recommendations
Routine screening is not typically recommended unless you exhibit risk factors such as:
- Family history of gallstones: Individuals with a family history of gallstones should consult their health care provider for personalized screening recommendations due to their increased risk.
- Overweight or obesity: Overweight or obese individuals are advised to undergo regular check-ups as their condition increases the likelihood of developing gallstones.
- Eating a high-fat diet: People consuming a high-fat diet should consider routine monitoring since this dietary habit significantly raises the risk of gallbladder issues.
- Diabetes: Regular screenings are recommended for individuals with diabetes because they are at a higher risk of gallbladder diseases.
During the procedure
Depending on your situation, your surgeon may use a minimally invasive or open surgical approach.
Minimally invasive surgery
During minimally invasive surgery, the surgeon makes small incisions in your abdomen.
The surgery is performed using tools that are placed through the small incisions.
Minimally invasive surgical approaches include laparoscopic and robotic surgery.
While there can be certain benefits to minimally invasive surgery, there are times when an open surgical approach may be best.
Open surgery
In some complex cases where minimally invasive surgery is not an option, traditional open surgery might be necessary.
During an open cholecystectomy, the surgeon makes a larger incision in your abdomen to remove the gallbladder.
Other related procedures
Whipple procedure
The Whipple procedure is a complex surgery that involves removing the head of the pancreas, duodenum, gallbladder, and bile ducts. This is typically performed for cancers, severe chronic pancreatitis, and other conditions affecting the pancreas, duodenum, and bile ducts.
Cholecystectomy is performed as part of the Whipple procedure, to remove the gallbladder.
While a Whipple procedure is a complex surgery, cholecystectomy on its own is much more common.
Liver transplant for cholangiocarcinoma
For people with bile duct cancer that is contained in the liver, liver removal and liver transplantation can be an effective treatment option.
Potential complications
While cholecystectomy is generally safe, potential complications may include:
- Infection: Post-surgical infection can occur at the incision site or internally, requiring antibiotics and sometimes additional medical intervention.
- Bile leakage: Bile may leak into the abdomen if the bile ducts are not properly sealed during surgery, leading to pain and potential infection.
- Injury to surrounding organs: Nearby organs such as the intestines, liver, or bile ducts may be accidentally injured during the procedure, causing further complications.
- Blood clots: Surgical procedures can increase the risk of blood clots forming in the legs or lungs, necessitating the use of blood thinners to prevent serious health issues.
Recovery
Post-operative care is essential for a smooth recovery.
Follow your surgeon’s instructions, which may include managing pain with prescribed medications, gradual return to physical activity, and a temporary special diet to ease digestive stress.
Prevention and healthy living
Preventing gallbladder issues can often be achieved through adopting a healthy lifestyle. Key methods include maintaining a healthy weight, as obesity significantly increases the risk of gallstones. Eating a balanced diet high in fiber and low in fat is crucial; a diet rich in fruits, vegetables and whole grains helps prevent the formation of gallstones.
Regular physical exercise not only aids in weight management but also enhances overall digestive health. Staying hydrated by drinking plenty of water supports bile production, reducing the risk of gallstone formation.
Additionally, avoiding rapid weight loss and extreme dieting can prevent gallstones since severe dietary restrictions might disrupt the balance of bile chemicals. Learn more about the importance of healthy bile ducts>>
Adhering to preventative measures can contribute significantly to maintaining optimal gallbladder health.
