Venous thoracic outlet syndrome (TOS) is a condition that occurs when the subclavian vein is compressed, leading to obstruction of blood flow from the arm to the heart.
This can result in pain, swelling, and possibly blood clots in the affected limb.
Venous TOS is often caused by repetitive activities, anatomical abnormalities, or trauma.
Accurate diagnosis through medical evaluation and imaging tests is essential for effective treatment, which may involve medications, thrombolysis, physical therapy, or surgery.
Thoracic outlet syndrome care at WashU Medicine

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What is venous thoracic outlet syndrome?
Venous thoracic outlet syndrome is a type of TOS characterized by compression of the subclavian vein.
This compression obstructs the blood flow, causing symptoms like swelling, pain, and even blood clots (deep vein thrombosis) in the arm.
Venous TOS requires prompt medical attention to prevent complications.
Learn more: What is thoracic outlet syndrome?
Venous TOS causes
Venous TOS can be caused by several factors, including:
Anatomical abnormalities
- Cervical ribs: Extra ribs can compress the subclavian vein.
- Fibromuscular bands: Tight bands of muscle or ligament may obstruct venous flow.
- Congenital defects: Structural abnormalities that are present from birth.
Trauma
- Injury: Trauma from accidents or falls can lead to compression and swelling that affects blood flow.
- Repetitive strain: Activities involving repetitive arm movements, like certain sports or work tasks, can cause venous TOS.
Poor posture
- Slouching: Poor posture that leads to drooping shoulders can compress the thoracic outlet.
- Prolonged postures: Staying in certain positions for long periods can worsen vein compression.
Other factors
- Obesity: Excess weight may increase pressure on the thoracic outlet.
- Tumors: Rarely, growths in the thoracic outlet may compress the subclavian vein.
Venous TOS symptoms
Symptoms of venous TOS can be severe and may require urgent medical attention, including:
Swelling
- Arm swelling: Noticeable swelling in the affected arm.
- Hand swelling: Swelling extending to the hand and fingers.
Pain
- Aching pain: Persistent pain in the arm or shoulder.
- Pain on exertion: Increased pain during physical activity.
Circulatory symptoms
- Discoloration: Bluish coloration of the affected arm and hand.
- Heaviness: Sensation of heaviness in the arm.
Blood clots
- Deep vein thrombosis (DVT): Formation of blood clots in the subclavian vein, which can lead to serious complications.
Venous TOS diagnosis
Diagnosing venous TOS involves several steps, including:
Medical history
Your doctor will take a detailed history of your symptoms, any previous injuries, and activities that may contribute to venous TOS.
Physical examination
A physical exam will assess swelling, pain, and discoloration in your arm and hand. Specific maneuvers may be used to reproduce symptoms and identify the compression site.
Imaging tests
Imaging tests such as these may be used:
- Ultrasound: To visualize the vein and detect blood clots or compression.
- Venogram: An X-ray of the veins using a contrast dye to highlight blood flow obstructions.
- MRI or CT scans: Detailed images to identify structural abnormalities causing vein compression.
Blood tests
Blood tests may be conducted to check for markers of inflammation or blood clotting disorders.
Venous TOS treatment
Treatment for VTOS depends on the severity of symptoms and underlying causes, and may include:
Conservative treatments
- Physical therapy: Exercises to improve posture, strengthen muscles, and reduce compression.
- Medications: Anti-inflammatory drugs and anticoagulants (blood thinners) to prevent blood clots and reduce symptoms.
Thrombolysis
- Procedure: If a blood clot is present, thrombolysis may be needed to dissolve the clot and restore normal blood flow.
Surgical treatment
In severe cases or when conservative treatments fail, surgery may be required:
- Venous decompression: Surgical removal of structures compressing the subclavian vein.
- First rib resection: Removal of the first rib to relieve compression.
- Scalenectomy: Removal or release of portions of the scalene muscles contributing to the compression.
Living with venous TOS
Managing venous TOS requires a comprehensive approach involving medical intervention, physical therapy, and lifestyle modifications. Maintaining good posture and avoiding activities that worsen symptoms are crucial.
Early diagnosis and treatment significantly improve outcomes and help prevent complications such as blood clots.
If you suspect you have venous TOS or have been diagnosed with the condition, seeking medical advice from a healthcare professional is essential. Appropriate treatment and management can effectively control symptoms and enhance your quality of life.
